PMC:7781431 / 34445-36506 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T344 0-10 Sentence denotes SARS-CoV-2
T345 11-297 Sentence denotes Severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) refers to a coronavirus strain that causes 2019 coronavirus disease (COVID-19), a respiratory disease that is the cause of the COVID-19 pandemic (Coronaviridae Study Group of the International Committee on Taxonomy of, 2020).
T346 298-426 Sentence denotes SARS-CoV-2 is an RNA virus that infects the lungs and causes deaths through complications such as cytokine storms (Goldin et al.
T347 427-433 Sentence denotes 2020).
T348 434-612 Sentence denotes The anti-inflammatory action of mesenchymal stem cells is well known, and it is believed that these mesenchymal stem cells exhibit anti-inflammatory action through PGE2 and LXA4.
T349 613-795 Sentence denotes These lipids mediators alleviate the SARS-CoV-2 cytokine storm, while arachidonic acid, dihomo-gamma-linolenic acid, and gamma-linolenic acid inactivate enveloped viruses (Das 2020).
T350 796-930 Sentence denotes Obesity is a risk factor for SARS-CoV-2 infection, and a BMI of 30 kg/m2 increases the risk of infection by 61% (Bello-Chavolla et al.
T351 931-937 Sentence denotes 2020).
T352 938-1086 Sentence denotes This is likely due to a deficiency of SPMs in obese patients, and this deficiency promotes adverse reactions during SARS-CoV-2 infection (Pal et al.
T353 1087-1093 Sentence denotes 2020).
T354 1094-1219 Sentence denotes LXA4, Elovanoid-N32 or RvD6 isomers reduced expression of angiotensin-converting enzyme 2 (ACE2), but NDP1 did not reduce it.
T355 1220-1390 Sentence denotes These lipids mediators also counteract the binding of the receptor-binding domain (RBD) of SARS-CoV-2 spike (S) protein to the injured cornea (Figs. 3 and 4) (Pham et al.
T356 1391-1397 Sentence denotes 2020).
T357 1398-1523 Sentence denotes Elovanoid-N32 or RvD6 isomers also attenuated the expression of cytokines involved in a cytokine storm and hyperinflammation.
T358 1524-1754 Sentence denotes Based on previous study results that have demonstrated SPMs as potential therapeutic targets for SARS-CoV-2 infection, studies and review on the use of fish oil, an SPMs precursor, as an adjuvant are in progress. (Torrinhas et al.
T359 1755-1774 Sentence denotes 2020; Rogero et al.
T360 1775-1781 Sentence denotes 2020).
T361 1782-2054 Sentence denotes SPMs and soluble epoxide hydrolase inhibitors are currently in clinical trials for other inflammatory diseases and can be quickly converted and used for SARS-CoV-2 management through the removal of cellular debris and inhibition of inflammatory cytokines (Panigrahy et al.
T362 2055-2061 Sentence denotes 2020).