PMC:7781431 / 33193-34443 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T330 0-146 Sentence denotes Hepatitis C virus (HCV) is a positive-sense single-stranded RNA virus of the family Flaviviridae with a small (55–65 nm size) envelope (Lee et al.
T331 147-153 Sentence denotes 2017).
T332 154-308 Sentence denotes The HCV is the cause of hepatitis C and some cancers such as liver cancer (hepatocellular carcinoma, abbreviated HCC) and lymphoma in humans (Ferri et al.
T333 309-337 Sentence denotes 2015; Rusyn and Lemon 2014).
T334 338-418 Sentence denotes To date, there appears to be no report on the effectiveness of SPMs against HCV.
T335 419-566 Sentence denotes However, HCV peptide (C5A), an amphiphilic α-helix peptide of HCV, is an activator of the N-formyl peptide receptor in human phagocytes (Lin et al.
T336 567-573 Sentence denotes 2011).
T337 574-664 Sentence denotes This suggests the possibility of interaction between RvD1 and LXA4, FPR families, and HCV.
T338 665-787 Sentence denotes Vitamin D metabolites inhibit HCV and upregulate GPR37 gene expression, which induces cellular autophagy (Gutierrez et al.
T339 788-794 Sentence denotes 2014).
T340 795-926 Sentence denotes PD1 was recently proposed as a new ligand for GPR37, and some studies suggest a possible relationship between PD1 and HCV (Fig. 4).
T341 927-1077 Sentence denotes SAA also has antiviral effects against HCV, however, it induces chronic inflammation through FPR2/ALX, causing liver damage (Abouelasrar Salama et al.
T342 1078-1084 Sentence denotes 2019).
T343 1085-1250 Sentence denotes Although research has not been conducted yet, RvD1 and LXA4, which inhibit the action of SAA, are likely to suppress liver damage caused by SAA during HCV infection.