| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T152 |
0-155 |
Sentence |
denotes |
Originally FPR2 was classified as an FPR receptor due to its activation by the low-affinity endogenous agonist N-formyl methionyl peptide (fMLP) (Ye et al. |
| T153 |
156-162 |
Sentence |
denotes |
1992). |
| T154 |
163-401 |
Sentence |
denotes |
The receptor was reclassified as FPR2/ALX, as LXA4 exhibited the highest affinity of all FPR2/ALX endogenous agonists through screening of various receptor ligands using radiolabelled [3H]-LXA4 and subsequent GTPase activity (Fiore et al. |
| T155 |
402-420 |
Sentence |
denotes |
1994; Brink et al. |
| T156 |
421-427 |
Sentence |
denotes |
2003). |
| T157 |
428-554 |
Sentence |
denotes |
Binding of LXA4 leads to the stimulation of monocyte chemotaxis, macrophage differentiation, and efferocytosis (Maderna et al. |
| T158 |
555-585 |
Sentence |
denotes |
2010; Maddox and Serhan 1996). |
| T159 |
586-710 |
Sentence |
denotes |
LXA4 also reduces the adaptive immune response by reducing memory B cell antibody production and proliferation (Ramon et al. |
| T160 |
711-717 |
Sentence |
denotes |
2014). |
