LitCovid-sentences  

PMC:7781431 / 14459-15811 JSONTXT 2 Projects

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Id Subject Object Predicate Lexical cue
T133 0-19 Sentence denotes Chemerin receptor 1
T134 20-211 Sentence denotes Chemerin receptor 1 (chemerin1, ChemR23, or ERV1) is expressed on a wide range of immune cells, including monocytes, macrophages, natural killer cells, bone marrow cells, and dendritic cells.
T135 212-298 Sentence denotes Besides, ERV1 has been identified in adipocytes and endothelial cells (Luangsay et al.
T136 299-305 Sentence denotes 2009).
T137 306-412 Sentence denotes ERV1 was initially classified as an orphan GPCR with homology to the formyl peptide receptor (Gantz et al.
T138 413-477 Sentence denotes 1996) and the anaphylatoxin C3a and C5a receptors (Samson et al.
T139 478-589 Sentence denotes 1998) until recently when it was discovered to be a receptor for the chemotactic protein chemerin (Meder et al.
T140 590-596 Sentence denotes 2003).
T141 597-737 Sentence denotes In addition to chemerin, RvE1 was identified as a second endogenous agonist through a screening program against the GPCR panel (Arita et al.
T142 738-744 Sentence denotes 2007).
T143 745-913 Sentence denotes ERV1 (chemokine like receptor 1, also known as CMKLR1) is a receptor for RvE1, which has been shown to bind more strongly than chemerin (a peptide ligand) (Arita et al.
T144 914-935 Sentence denotes 2005; Wittamer et al.
T145 936-942 Sentence denotes 2004).
T146 943-1098 Sentence denotes ERV1 overexpressing mice showed a large increase in phagocytosis upon decreased neutrophil inhibition and decreased neutrophil infiltration (Herrera et al.
T147 1099-1105 Sentence denotes 2015).
T148 1106-1208 Sentence denotes Also, RvE2 is a partial agonist compared to RvE1 in CHO-chemerin1 β-arrestin recruitment (Isobe et al.
T149 1209-1216 Sentence denotes 2012a).
T150 1217-1352 Sentence denotes However, since there is no additional information on this ligand, further investigation of potential ligand-receptor pairs is required.