PMC:7736111 / 95586-97026 JSONTXT 2 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T563 0-132 Sentence denotes Similarly, Zhao et al. (2020) studied antibody response in 173 clinically diagnosed COVID-19 patients with a median age of 48 years.
T564 133-285 Sentence denotes Among these, nine patients (three critical and six non-critical) studied longitudinally for the relation of antibody response with the disease severity.
T565 286-365 Sentence denotes Antibody titer was higher in the critical patients as compared to non-critical.
T566 366-579 Sentence denotes This higher titer of antibodies was not reflected by the clearance of the virus, thus suggesting that antibody response in critical cases may be associated with worse disease outcome rather than protective effect.
T567 580-677 Sentence denotes However, like other studies, this study also suffers from the same limitation of low sample size.
T568 678-892 Sentence denotes In line with the notion that antibody response is higher in severe patients, a large population study (n = 30,576 persons from Iceland) (Gudbjartsson et al., 2020) conducted in Iceland revealed similar observation.
T569 893-1081 Sentence denotes The study provided a comprehensive account of the relation of antibody response concerning age, sex, body-mass index, drugs habits like smoking and the use of anti-inflammatory medication.
T570 1082-1250 Sentence denotes Results show that patients with smoking habit and who were on anti-inflammatory medication, had lower antibody levels, while body mass index had a positive association.
T571 1251-1440 Sentence denotes The data thus suggest that antibody response may not always favor clearance of the virus, but in some instances, higher antibody levels may make the patients more vulnerable to the disease.