| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T45 |
0-222 |
Sentence |
denotes |
Preceding studies on human infecting coronaviruses (CoVs) have demonstrated a critical role of nucleic acid-sensing (NAS) pathways in recognizing various components of these viruses to initiate an early antiviral response. |
| T46 |
223-371 |
Sentence |
denotes |
Whereas, potent inhibitory mechanisms are developed by CoVs to prevent or delay early antiviral responses (Rose et al., 2010; Adedeji et al., 2013). |
| T47 |
372-470 |
Sentence |
denotes |
These inhibitory signals affect a range of host defense pathways to allow the propagation of CoVs. |
| T48 |
471-573 |
Sentence |
denotes |
Some inhibitory signals may even activate cell death pathway to induce a robust proinflammatory state. |
| T49 |
574-901 |
Sentence |
denotes |
Studies from in vitro cell culture, animal models, and patients who have successfully recovered from SARS-CoV infection have provided detailed molecular insights about signaling molecules implicated in virus-host interaction that may also serve as a model to understand a similar process in SARS-CoV-2 (Totura and Baric, 2012). |
