| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T445 |
0-183 |
Sentence |
denotes |
Similarly, Zhou et al. (2020b) reported hyperactivated TH1 cell response with increased secretion of IFN-γ, GM-CSF, and IL-6 and with more robust expression in ICU cases than non-ICU. |
| T446 |
184-484 |
Sentence |
denotes |
Considering the age, gender and other associated factors, a large number of other studies have now confirmed that COVID-19 patients have increased levels of TH1 specific cytokines, with more robust levels seen in severe than mild cases (Huang C. et al., 2020; Xu Z. et al., 2020; Zhou et al., 2020b). |
| T447 |
485-626 |
Sentence |
denotes |
Similarly, CD8+ T cell-specific cytokines increased in COVID-19 patients, more pronounced in severe than mild condition (Zhou et al., 2020b). |
| T448 |
627-774 |
Sentence |
denotes |
Increased expression of GM-CSF was found in CD8+ T cells from ICU patients than non-ICU, while no difference was observed in IL-6 and TNF-α levels. |
| T449 |
775-1072 |
Sentence |
denotes |
PBMCs derived from COVID-19 patients and stimulated in vitro showed an increase in expression of CCL2, CXCL10, Eotaxin, and IL-1RA, and stimulation of CD8+ T cells were associated with an increase in IFN-γ levels, which indicates the functional responsiveness of these cells (Mathew et al., 2020). |
| T450 |
1073-1174 |
Sentence |
denotes |
These studies thus suggest a robust activation of TH1 specific and CD8+ T cells in COVID-19 patients. |
