PMC:7736111 / 40394-40989 JSONTXT 2 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T230 0-193 Sentence denotes Consistent with the low circulating levels of IFNs, transcriptional analysis of post-mortem lung samples further confirmed these observations and revealed no detectable type I or Type III IFNs.
T231 194-351 Sentence denotes Among the SARS-CoV-2 proteins which directly interfere with IFN response, ORF6, ORF8, and N protein inhibit IFN-β and NF-κB signaling (Li J.Y. et al., 2020).
T232 352-478 Sentence denotes Further, Konno et al. (2020) have identified a more extended variant of ORF3b with presumably more vigorous anti-IFN activity.
T233 479-595 Sentence denotes Thus, these early observations may point towards an impaired early IFN response by the host cells against SARS-CoV-2