PMC:7736111 / 146608-147639 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1016 0-90 Sentence denotes Recovery from ARDS is possible but only before the disease progresses to a critical stage.
T1017 91-246 Sentence denotes However, a mortality rate between 35 and 40% in ARDS patients demonstrates irreversible tissue damage manifested by tissue fibrosis (Bellani et al., 2016).
T1018 247-324 Sentence denotes TGF-β plays a central role in the late onset of fibrotic changes during ARDS.
T1019 325-586 Sentence denotes Acting with other proinflammatory molecules, TGF-β induces fibroblast cell proliferation and activation, collagen synthesis and deposition, synthesis of fibronectin, and alpha-smooth muscle actin, which all together contribute to fibrosis (Fan E. et al., 2020).
T1020 587-774 Sentence denotes Emerging histological studies from deceased COVID-19 patients reveal robust structural changes in the lungs and associated organs like the liver, kidneys, and heart (George et al., 2020).
T1021 775-1031 Sentence denotes Lung biopsy samples from a 50-year-old patient who had succumbed to COVID-19 revealed hyaline membrane formation, desquamation of epithelial and endothelial cells, mononuclear infiltration, and robust ATII cell damage, indicating ARDS (Xu Z. et al., 2020).