| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T632 |
0-303 |
Sentence |
denotes |
In another study on 30 COVID-19 patients with a varied range of disease severity from mild, moderate to severe, a reduction in the total peripheral blood NKT cells was seen across groups, with no difference in the overall number between ICU (n = 10) and non-ICU patients (n = 11) (Mazzoni et al., 2020). |
| T633 |
304-510 |
Sentence |
denotes |
Similarly, a study by Jouan et al. (2020) found a decrease in NKT and MAIT cells in the peripheral blood of COVID-19 patients (n = 30, with varied disease severity) as compared to healthy controls (n = 20). |
| T634 |
511-786 |
Sentence |
denotes |
This decline in circulating MAIT cells was concomitantly associated with an increase in these cells in the endotracheal aspirates (ETA) obtained from critically ill patients who needed mechanical ventilation (n = 12), while no changes in NKT cell number in ETA were detected. |
| T635 |
787-946 |
Sentence |
denotes |
The presence of circulating IL-18 reflected the activation of these cells, and the expression of PD-1 suggested subsequent exhaustion throughout the infection. |
| T636 |
947-1104 |
Sentence |
denotes |
This study thus indicates that the presence of the activated status of these unconventional T cells may serve as a predictive assessment of disease severity. |
| T637 |
1105-1340 |
Sentence |
denotes |
More research about the activation, proliferation and differentiation status of these cells to the disease severity and local vs systemic effect is needed to fully understand their contribution in COVID-19 (Chen and John Wherry, 2020). |
