| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T449 |
0-320 |
Sentence |
denotes |
Historical data indicated that CoVs, which infect humans by using a specific host protein as a primary receptor, including HCoV-229E (APN), HCoV-NL63 (ACE2), SARS-CoV (ACE2), SARS-CoV-2 (ACE2) and MERS-CoV (DDP4), originated from bats, whereas HCoV-OC43 and HCoV-HKU1, which use Neu5,9Ac2, originated from rodents [255]. |
| T450 |
321-424 |
Sentence |
denotes |
In contrast, IAVs infecting humans using sialyl glycans are thought to have originated from wild birds. |
| T451 |
425-872 |
Sentence |
denotes |
The finding that some H16 HAs isolated from wild birds contain Y98F, being different from HAs of other Sia-binding IAVs but the same as bat non-Sia-binding HAs of H17 and H18 IAVs, and the finding that there are bat α2,3Sia-binding IAV isolates that are phylogenetically different from other identified IAVs with HA closest to mallard H9 viruses indicate the possibility of cross wild bird-to-bat and/or bat-to-wild bird transmission of IAVs [64]. |
| T452 |
873-989 |
Sentence |
denotes |
Studies on evolutional changes of wild bird IAVs and bat IAVs may lead to clarification of the host origins of IAVs. |
| T453 |
990-1162 |
Sentence |
denotes |
An understanding of viral adaptation in the wild animals to recognize distinct receptors may lead to the establishment of strategies for efficient control of CoVs and IAVs. |
