PMC:7712180 / 76070-78258 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T401 0-298 Sentence denotes A novel CoV was first isolated from the sputum of a Saudi Arabian patient who died from acute respiratory distress syndrome (ARDS) and subsequent multiorgan dysfunction syndrome (MODS) in 2012 [246], and the novel CoV was named Middle East respiratory syndrome coronavirus, MERS-CoV, in 2013 [247].
T402 299-407 Sentence denotes Most infected patients present with atypical pneumonia that has the potential to progress to ARDS [104,247].
T403 408-546 Sentence denotes Although confined to the Middle East, mainly in Saudi Arabia, human MERS-CoV infection spread to 27 other countries from people traveling.
T404 547-668 Sentence denotes As of May 2020, 2562 cases with 881 deaths have been reported to WHO, the case-fatality rate being approximately 34% [8].
T405 669-913 Sentence denotes New MERS-CoV infection cases caused by direct or indirect contact with infected dromedary camels (Camelus dromedaries) or by close contact with infected humans have continued to be reported, and MERS is thus still a disease of a global concern.
T406 914-1063 Sentence denotes By comparing ∼30-kb genome sequences, MERS-CoVs isolated from patients were reported to share more than 99% nt identity to dromedary MERS-CoVs [248].
T407 1064-1378 Sentence denotes Based on results of nt sequence and phylogenetic analyses, MERS-CoVs are closely related to several lineage C βCoVs/RNA detected in feces of different bat species but have 100% nt identity to a CoV gene fragment (only 182 nucleotides) isolated from Taphozous perforatus bat feces in Bisha, Kingdom of Saudi Arabia.
T408 1379-1604 Sentence denotes Based on complete genome sequences that have been so far been determined, the most closely related virus sharing about 85.6% nt identity to MERS-CoV is NeoCoV isolated from Neoromicia capensis bat feces in South Africa [106].
T409 1605-1705 Sentence denotes Dromedary camels are the only confirmed hosts of zoonotic MERS-CoV leading to human infection [111].
T410 1706-2055 Sentence denotes MERS-CoV or its RNA can be detected in dromedary nasal swabs and lung tissue samples, and an experimental study showed that MERS-CoV appears to cause mild upper respiratory tract disease in dromedary camels [109,110], suggesting that dromedary MERS-CoV is transmitted through droplets (either droplet particles or droplet nuclei) and contact routes.
T411 2056-2188 Sentence denotes These findings suggested that bats are ancestral reservoir hosts and dromedary camels are intermediate reservoir hosts of MERS-CoVs.