Id |
Subject |
Object |
Predicate |
Lexical cue |
T401 |
0-298 |
Sentence |
denotes |
A novel CoV was first isolated from the sputum of a Saudi Arabian patient who died from acute respiratory distress syndrome (ARDS) and subsequent multiorgan dysfunction syndrome (MODS) in 2012 [246], and the novel CoV was named Middle East respiratory syndrome coronavirus, MERS-CoV, in 2013 [247]. |
T402 |
299-407 |
Sentence |
denotes |
Most infected patients present with atypical pneumonia that has the potential to progress to ARDS [104,247]. |
T403 |
408-546 |
Sentence |
denotes |
Although confined to the Middle East, mainly in Saudi Arabia, human MERS-CoV infection spread to 27 other countries from people traveling. |
T404 |
547-668 |
Sentence |
denotes |
As of May 2020, 2562 cases with 881 deaths have been reported to WHO, the case-fatality rate being approximately 34% [8]. |
T405 |
669-913 |
Sentence |
denotes |
New MERS-CoV infection cases caused by direct or indirect contact with infected dromedary camels (Camelus dromedaries) or by close contact with infected humans have continued to be reported, and MERS is thus still a disease of a global concern. |
T406 |
914-1063 |
Sentence |
denotes |
By comparing ∼30-kb genome sequences, MERS-CoVs isolated from patients were reported to share more than 99% nt identity to dromedary MERS-CoVs [248]. |
T407 |
1064-1378 |
Sentence |
denotes |
Based on results of nt sequence and phylogenetic analyses, MERS-CoVs are closely related to several lineage C βCoVs/RNA detected in feces of different bat species but have 100% nt identity to a CoV gene fragment (only 182 nucleotides) isolated from Taphozous perforatus bat feces in Bisha, Kingdom of Saudi Arabia. |
T408 |
1379-1604 |
Sentence |
denotes |
Based on complete genome sequences that have been so far been determined, the most closely related virus sharing about 85.6% nt identity to MERS-CoV is NeoCoV isolated from Neoromicia capensis bat feces in South Africa [106]. |
T409 |
1605-1705 |
Sentence |
denotes |
Dromedary camels are the only confirmed hosts of zoonotic MERS-CoV leading to human infection [111]. |
T410 |
1706-2055 |
Sentence |
denotes |
MERS-CoV or its RNA can be detected in dromedary nasal swabs and lung tissue samples, and an experimental study showed that MERS-CoV appears to cause mild upper respiratory tract disease in dromedary camels [109,110], suggesting that dromedary MERS-CoV is transmitted through droplets (either droplet particles or droplet nuclei) and contact routes. |
T411 |
2056-2188 |
Sentence |
denotes |
These findings suggested that bats are ancestral reservoir hosts and dromedary camels are intermediate reservoir hosts of MERS-CoVs. |