PMC:7712180 / 61531-62682 JSONTXT 2 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T322 0-560 Sentence denotes Analysis of whole-genome sequences showed that SARS-CoV-2 shares about 96.1% identity to a bat SARSr-CoV isolated from Rhinolophus affinis (Ra) in Yunnan, China in 2013 (BatCoV RaTG13) [132,133], 93.3% identity to a bat SARSr-CoV isolated from Rhinolophus malayanus (Rm) in Yunnan (YN), China in 2019 (BetaCoV/Rm/Yunnan/YN02/2019, RmYN02) [133], and 87.8% and 87.6% identity to two bat SARSr-CoVs, BatCoV RpZC45 and BatCoV RpZXC21, respectively, detected in Rhinolophus pusillus (Rp) bats from Zhoushan City (ZXC or ZC), Zhejiang Province, China in 2015 [226].
T323 561-684 Sentence denotes As was the case for SARS-CoV, SARS-CoV-2 is likely to have originated from Chinese horseshoe bats in the genus Rhinolophus.
T324 685-968 Sentence denotes Although there is high sequence identity between the longest encoding gene region (1ab) of RmYN02 and 1ab of SARS-CoV-2 (nt 97.2%, aa 98.8%), there is low sequence identity between the SARS-CoV-2 S RBD and RaTG13 S RBD (nt 85.3%, aa 89.3%) or RmYN02 S RBD (nt 61.3%, aa 62.4%) [133].
T325 969-1151 Sentence denotes The RBD is a major determinant of host range and it is therefore likely that there is an intermediate host facilitating a bat SARSr-CoV to acquire efficient ability to infect humans.