| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T240 |
0-575 |
Sentence |
denotes |
HCoV-229E was first recorded in the mid-1960s by two different groups in different countries: (i) Tyrrell and Bynoe [200] isolated the virus in a research unit in Salisbury, Wilts, England, and most of their work was done with a nasal swab of number B814 from a volunteer boy with a common cold and (ii) Hamre and Procknow isolated the virus from five medical students, including four students with mild upper respiratory illnesses (URIs) and one healthy student, using acute URI specimen number 229E as the prototype strain in the University of Chicago, United States [201]. |
| T241 |
576-975 |
Sentence |
denotes |
Recently, investigation of the ancestral origins of the virus revealed that HCoV-229E has a high genetic identity to GhanaBt-CoVGrp1, a member of the bat CoV group (lineage) 1 that was isolated from fecal samples but was not found in oral swabs from insect-eating leaf-nosed bats, Hipposidero (H.) caffer (cf.) ruber [125,126] and H. abae, but not H. jonesi and H. cf. gigas [126], in Ghana, Africa. |
| T242 |
976-1118 |
Sentence |
denotes |
Results of molecular clock analyses indicated that HCoV-229E and GhanaBt-CoVGrp1 shared an old ancestor in approximately 1686–1800 C.E. [125]. |
| T243 |
1119-1371 |
Sentence |
denotes |
In generic CoV RT-PCR screening, nasal swabs, but not fecal samples, from dromedary camels in Kenya and the Kingdom of Saudi Arabia (KSA) were positive for HCoV229E–related CoV (camelid-229E CoV), suggesting that the viruses are endemic in dromedaries. |
| T244 |
1372-1505 |
Sentence |
denotes |
The results of genomic and phylogenetic analyses suggested that both human-derived and dromedary-derived CoVs are monophyletic [202]. |
| T245 |
1506-1772 |
Sentence |
denotes |
The findings provide important implications for the emergence of HCoV-229E evolving from HCoV-229E-related CoVs (bat-229E CoVs) in bats of the genus Hipposideros in Africa as natural hosts [125,126] via dromedary camels in Africa and KSA as intermediate hosts [202]. |
