LitCovid-sentences  

PMC:7712180 / 3117-6343 JSONTXT 3 Projects

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Id Subject Object Predicate Lexical cue
T18 0-368 Sentence denotes Of the three genera of IVs, alpha IVs (IAVs), beta IVs (IBVs) and gamma IVs (ICVs), that infect humans, eight segmented (−)ssRNA-containing IAVs (A/H3N2/68 and A/H1N1/09 variants) and IBVs (B/Yamagata and B/Victoria lineage-like viruses) with hemagglutinin (HA) spikes cause seasonal influenza epidemics that spread rapidly and cause mild to severe or fatal illnesses.
T19 369-568 Sentence denotes Seasonal influenza vaccines and anti-influenza drugs against IAVs and IBVs are available, but seasonal influenza still causes up to 5 million severe illnesses and up to 650,000 deaths each year [12].
T20 569-642 Sentence denotes Thus, epidemics of IAVs and IBVs are important public health issues [12].
T21 643-864 Sentence denotes Seven segmented (−)ssRNA-containing ICVs with hemagglutinin-esterase-fusion (HEF) spikes usually cause mild upper respiratory disease but can cause lower respiratory disease in children and severe illness in infants [13].
T22 865-984 Sentence denotes Other seven segmented (−)ssRNA-containing IDVs with HEF spikes mainly infect cattle and cause respiratory illness [14].
T23 985-1114 Sentence denotes These IDVs seem to have a zoonotic potential to infect humans, but whether they can cause illness in humans remains unknown [15].
T24 1115-1258 Sentence denotes Among all known influenza viruses, only IAVs are subtyped according to their HAs (H) and neuraminidase (NA or N) spikes into H1–H18 and N1–N11.
T25 1259-1453 Sentence denotes Several subtypes of IAVs, including H1N1, H3N2 and H5N1, have crossed the species barrier to infect a variety of birds and mammals including humans, indicating that they have zoonotic potential.
T26 1454-1548 Sentence denotes IAVs not only mutate quickly but also prefer to reassort with other IAVs to form a new strain.
T27 1549-1636 Sentence denotes Due to these properties, IAVs have caused four pandemics in the past 102 years [10,16].
T28 1637-1695 Sentence denotes These viruses continued to threat human health seasonally.
T29 1696-1948 Sentence denotes However, the first recorded pandemic virus, A/H1N1/1918-derived virus, disappeared from human circulation after the appearance of the A/H2N2/1957 pandemic virus containing five gene segments (PB2, PA, NP, M and NS) from human A/H1N1/1918-derived virus.
T30 1949-2143 Sentence denotes Similarly, A/H2N2/1957-derived virus disappeared after the appearance of A/H3N2/1968 pandemic virus containing six gene segments (PB2, PA, NP, NA, M and NS) from human A/H2N2/1957-derived virus.
T31 2144-2415 Sentence denotes In 1977, A/H1N1/1918-derived virus reemerged, probably due to accidental release from a laboratory, as a low-grade A/H1N1/1977 pandemic virus that primarily affected young immunologically naïve people [17,18] who were born after the end of the H1 period (1957 and later).
T32 2416-2529 Sentence denotes This resulted in two subtypes of IAVs circulating in humans, A/H1N1/1977-derived and A/H3N2/1968-derived viruses.
T33 2530-2886 Sentence denotes After the appearance of the A/H1N1/2009 pandemic virus containing one human gene segment (PB1) from A/H3N2/1968-derived virus and three gene segments (H1, NP and NS) from classical swine A/H1N1 virus believed to have been transmitted from A/H1N1/1918-derived virus between 1918 and 1920, A/H1N1/1977-derived virus disappeared from human circulation [4,19].
T34 2887-3023 Sentence denotes The disappearance of that virus resulted in only A/H1N1/2009-derived and A/H3N2/1968-derived viruses remaining in circulation in humans.
T35 3024-3226 Sentence denotes Thus, IAVs are important not only because human IAVs cause seasonal influenza but also because nonhuman IAVs cause farm animal diseases, sporadic zoonotic outbreaks and periodic unpredictable pandemics.