LitCovid-sentences  

PMC:7712180 / 106670-111564 JSONTXT 3 Projects

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Id Subject Object Predicate Lexical cue
T584 0-127 Sentence denotes Family Genus Genome Type Host IAV Subtype or IBV1/ICV/IDV Lineage Disease Receptor-binding Protein Host Receptor Ref.
T585 128-471 Sentence denotes Birds Wild birds (frequently found in waterfowls and shorebirds) H1–H16 and N1–N9HP: H5NX, X = NA subtypes No or mild diseaseHP: isolated from dead wild birds HA TerminalNeu5Acα2,3GalSome gull/tern H16: α2,6Neu5Ac ≥ α2,3Neu5AcInternalDuck type: non-fucosylate, SiaLec, 3′SLNGull type: fucosylated, SiaLex and 6-sulfo-SiaLex Gull/tern H16:
T586 472-534 Sentence denotes 6′SLDN ≥ LSTb, but some 6-sulfo-SiaLex > 6′SLDN, LSTb [23,24]
T587 535-687 Sentence denotes Domestic birds (poultry) H1–H13, N1–N9 LP: mild disease HP: multi-organ systemic disease HA TerminalNeu5Acα2,3GalInternalHP higher affinity than LP:
T588 688-715 Sentence denotes 3′SLN, SiaLecAll LP and HP:
T589 716-774 Sentence denotes 3′SLN > SiaLex, SiaLec > SiaLea, 3′SLN ~ SiaLecH5 poultry:
T590 775-810 Sentence denotes 6-sulfo-3′SLNH7H7 from all species:
T591 811-901 Sentence denotes 6-sulfo-3′SLN, 6-sulfo-SiaLex > nonsulfated SGPs [25,26,27,28,29,30,31,32,33,34,35,36,37]
T592 902-968 Sentence denotes Domestic ducks HP: H5N1, H5N2, H5N3, H5N5, H5N6, H5N8, H7N2, H7N9
T593 969-1058 Sentence denotes Other poultry HP: H5N1, H5N2, H5N3, H5N6, H5N8, H5N9, H7N1, H7N2, H7N3, H7N4, H7N7, H7N9
T594 1059-1233 Sentence denotes Alphainfluenzavirus Other animals Pigs H1N1, H1N2, H2N3, H3N1, H3N2, HPH5N1 Respiratory disease HA Neu5Acα2,6Gal > Neu5Acα2,3GalNeu5AcGM3, Neu5GcGM3 [4][38,39,40,41]
T595 1234-1342 Sentence denotes Horses H7N7, H3N8 Respiratory disease HA Mainly Neu5Gcα2,3Gal, Sialyllacto-N-tetraose a, SiaLex [42,43]
T596 1343-1449 Sentence denotes 8 (−)ssRNA segments Dogs H3N8, H3N2, H3N1, H5N2, HPAI H5N1, H1N1 Respiratory disease HA Canine H3N8:
T597 1450-1502 Sentence denotes 6-sulfo-3′SLN and Neu5Acα2,3Galβ- [38][43,44,45,46]
T598 1503-1566 Sentence denotes Cats H7N2, H3N2, HPH5N1 Respiratory disease HA Feline H7N2:
T599 1567-1590 Sentence denotes Siaα2,3Gal [38,47][48]
T600 1591-1759 Sentence denotes A Ferrets(a model for human infection and transmission) Triple reassortant H1N1 SIV, A(H1N1)pdm09 Respiratory disease HA Expected to bind to Neu5Acα2,6Gal [49,50]
T601 1760-1942 Sentence denotes Occasionally in numerous species of mammals such as whales, seals, tigers, and minks Seal H7N7 & whale H13N9Tiger HPH5N1 Mink H9N2 Respiratory disease HA Seal H7N7 & whale H13N9:
T602 1943-2110 Sentence denotes Siaα2,3GalTiger HPH5N1 HA with Q226 and G228 (H3 numbering): predicted to prefer Siaα2,3GalMink H9N2 HA with 226L: increased binding to Siaα2,6Gal [51,52,53,54,55,56]
T603 2111-2517 Sentence denotes Orthomyxoviridae Zoonosis Poultry, pigs and other animals H1, H2, H3, H5 (HP & LP), H6, H7 (HP & LP), H9, H10 HP: severe systemic diseaseOther zoonotic infections: ranging from mild upper respiratory tract infection to severe pneumonia and death.Possible to cause conjunctivitis, GI symptoms, encephalitis and encephalopathy HA Most still retains previous host-receptor specificity [16][57,58,59]
T604 2518-2887 Sentence denotes Humans 1918-derived H1N1 (extinct), 1957-derived H2N2 (extinct), 1968-derived H3N2, 2009-derived H1N1 Pandemic and continued as seasonal flu:Primarily cause respiratory disease (usually pdm more severe, including pneumonia) HA Terminal Neu5Acα2,6GalInternal 6′S(LN)nEarly human-adapted viruses: n = 1, 2, 3, etc.Long-term circulating viruses: n ≥ 3 [16,19][60,61]
T605 2888-2964 Sentence denotes Bats Fruit-eating bats in Guatemala Sl-BatH17N10Fruit-eating bats in Peru:
T606 2965-3109 Sentence denotes Ap-batH18N11 H17: liver, intestine, lung and kidney tissues, and rectal swabsH18: intestine tissue and rectal swabs HA MHC-II HLA-DR [62,63]
T607 3110-3167 Sentence denotes Fruit-eating bats in Egypt Distinct from all known IAVs.
T608 3168-3349 Sentence denotes HAs, closest to mallard H9 viruses with 73% aa identity Viruses in bat oral swabs > in rectal swabsAble to replicate in mouse lungs HA TerminalNeu5Acα2,3Gal > Neu5Acα2,6Gal [64]
T609 3350-3458 Sentence denotes Betainfluenzavirus 8 (-)ssRNA segments B Humans, sporadically in seals, pigs, horses, pheasants and dogs.
T610 3460-3715 Sentence denotes Influenza B viruses (IBVs)2 lineages- Victoria lineage B/Victoria/2/87-like viruses- Yamagata lineage: B/Yamagata/16/88-like viruses Seasonal flu HA Wild types of both Yamagata (HA with F95 and N194) and Victoria (HA with G141, R162 and D196) lineages:
T611 3716-3862 Sentence denotes Neu5Acα2,6Gal>Neu5Acα2,3Gal2001–2007 clinical isolates in Taiwan:83% of Yamagata-like strains prefer α2,6Sia; 17% prefer both α2,3Sia and α2,6Sia.
T612 3863-4150 Sentence denotes 54% of Victoria-like strains prefer both α2,3Sia and α2,6Sia; 25% prefer sulfated glycan, either β-Gal-3-sulfate or 6-HSO3-Galβ1,4GlcNAc; 21% prefer α2,6Sia.Dual α2,3Sia and α2,6Sia-binding viruses seem to be associated with bronchopneumonia and gastrointestinal symptoms. [65,66,67,68]
T613 4151-4438 Sentence denotes Gammainfluenzavirus 7 (−)ssRNA segments C Humans (particularly in infants and children), pigs, cattle Influenza C viruses (ICVs)6 lineages: C/Taylor, C/Mississippi, C/Aichi, C/Yamagata, C/Kanagawa and C/Sao Paulo Usually mild flu HEF TerminalC/Johannesburg/1/66 (C/Aichi lineage):
T614 4439-4470 Sentence denotes Neu5,9Ac2α2,6Gal [69,70,71,72]
T615 4471-4759 Sentence denotes Deltainfluenzavirus 7 (−)ssRNA segments D Pigs, cattle,91% seropositivity found among persons working with cattle Influenza D viruses (IDVs)3 lineages: D/OK, D/660 and D/JapaneseD/Japanese lineage contains 2 sublineages: D/Yama2016 and D/Yama2019 Usually mild flu HEF TerminalD/OK:
T616 4760-4825 Sentence denotes Neu5,9Ac2 and Neu5Gc9Ac either linked to α2,6Gal or α2,3GalD/660:
T617 4826-4894 Sentence denotes Neu5,9Ac2α2,6Gal, Neu5Gc9Acα2,6Gal and Neu5Gc9Acα2,3Gal [15,72][73]