Id |
Subject |
Object |
Predicate |
Lexical cue |
T29 |
0-194 |
Sentence |
denotes |
These are water-soluble molecules and, for their chemical nature, can pass the cell membranes; however, the presence of the hydroxyl group in the HCQ makes it more polar and less lipophilic [8]. |
T30 |
195-347 |
Sentence |
denotes |
Moreover, the accumulation of CQ and HCQ in intracellular compartments is due principally to the side chain and both have enantiomers (R and S isomers). |
T31 |
348-452 |
Sentence |
denotes |
Researches also demonstrated that the R-HCQ is present in the blood at higher concentrations than S-HCQ. |
T32 |
453-545 |
Sentence |
denotes |
These results suggested the stereoselective processes in the metabolism of the molecule [9]. |