PMC:7696151 / 3520-4065 JSONTXT 2 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T29 0-194 Sentence denotes These are water-soluble molecules and, for their chemical nature, can pass the cell membranes; however, the presence of the hydroxyl group in the HCQ makes it more polar and less lipophilic [8].
T30 195-347 Sentence denotes Moreover, the accumulation of CQ and HCQ in intracellular compartments is due principally to the side chain and both have enantiomers (R and S isomers).
T31 348-452 Sentence denotes Researches also demonstrated that the R-HCQ is present in the blood at higher concentrations than S-HCQ.
T32 453-545 Sentence denotes These results suggested the stereoselective processes in the metabolism of the molecule [9].