PMC:7652766 / 92102-93050 JSONTXT 2 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T449 0-91 Sentence denotes Remdesivir (RDV) is also among the several potential drugs tested for SARS-CoV-2 treatment.
T450 92-266 Sentence denotes Originally developed to treat Ebola virus infection, RDV is active against RNA viruses from different families, including Coronaviridae (e.g., SARS-CoV-1 and MERS-CoV) (325).
T451 267-344 Sentence denotes RDV showed an in vitro effective antiviral activity against SARS-CoV-2 (326).
T452 345-570 Sentence denotes Grein et al. (327) conducted a cohort study with 53 COVID-19 patients treated with RDV and found that 68% of them had improved oxygen-support class, whereas 57% of the patients receiving mechanical ventilation were extubated.
T453 571-721 Sentence denotes Overall mortality reached 13% over a median follow-up of 18 days, however, viral load data were not collected to confirm the antiviral effects of RDV.
T454 722-948 Sentence denotes The biggest issue with this study is that the authors did not include a group without RDV, which hampers the performance of comparative statistical analyses to prove whether the data found resulted from the treatment with RDV.