| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T402 |
0-121 |
Sentence |
denotes |
There are currently two clinical trials underway that aim to infuse Treg cells in patients with severe COVID-19 and ARDS. |
| T403 |
122-306 |
Sentence |
denotes |
The first one is a multi-center, prospective, double-blinded, placebo-controlled phase 1 randomized clinical trial, which has 45 patients who will receive cryopreserved UBC-Treg (288). |
| T404 |
307-487 |
Sentence |
denotes |
The second one is a randomized, double-blind, placebo-controlled phase 2 study with 88 participants who will receive off-the-shelf allogeneic hybrid Treg/Th2 cells (RAPA-501-ALLO). |
| T405 |
488-615 |
Sentence |
denotes |
RAPA-501-ALLO cells will be generated from healthy donors, cryopreserved, banked, and made available for off-the-shelf therapy. |
| T406 |
616-846 |
Sentence |
denotes |
The cells are manipulated ex vivo to differentiate into two anti-inflammatory phenotypes simultaneously, generating hybrid Treg/Th2 cells, with the potential to reduce inflammation and mediate a protective effect on tissues (289). |
