| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T360 |
0-305 |
Sentence |
denotes |
Although some studies found considerable clinical improvements resulting from treatment with IL-6 blockers (236–239), others do not report any significant difference between the clinical features of groups treated with anti-IL6/IL-6R mAbs and their respective controls (without anti-IL-6/IL-6R) (240–243). |
| T361 |
306-531 |
Sentence |
denotes |
These controversial results can be explained by the pleiotropic function of IL-6, which also play an important anti-inflammatory role, questioning the use of IL-6 blockade to suppress inflammation-induced tissue damage (244). |
| T362 |
532-734 |
Sentence |
denotes |
Additionally, severe side effects have been associated with the use of IL-6 blockers, including enhanced hepatic enzymes, thrombocytopenia, severe bacterial and fungal infections, and sepsis (241, 245). |
| T363 |
735-834 |
Sentence |
denotes |
In general, data from analyses on the use of this type of mAbs remain inconclusive (243, 246, 247). |
