PMC:7652766 / 63789-64983 JSONTXT 2 Projects

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Id Subject Object Predicate Lexical cue
T308 0-198 Sentence denotes The appearance of IgG near the third stage of the disease may be related to the clinical evolution of patients and those who fail to establish an efficient immune response might be at risk of death.
T309 199-343 Sentence denotes Interestingly, Guo et al. (197) found that approximately 22% of COVID-19 patients confirmed by RTq-PCR did not present detectable levels of IgM.
T310 344-543 Sentence denotes Most of these individuals were tested in the first seven days after the onset of symptoms, therefore the lack of IgM can be justified by the delay in generating a humoral response against SARS-CoV-2.
T311 544-678 Sentence denotes However, some critically ill patients followed for a longer period remained negative for IgM even 22 days after the onset of symptoms.
T312 679-921 Sentence denotes As for IgG levels, some patients took 30 to 40 days after the appearance of symptoms to show some detectable level of IgG, suggesting a possible failure in the production of antibodies that may have contributed to the severity of the disease.
T313 922-1194 Sentence denotes It is possible that the generation of antibodies in more advanced stages of COVID-19 does not benefit the recovery process since most pathological mechanisms at this stage might be more related to the excess of inflammatory mediators than the presence of the virus itself.