PMC:7652766 / 59554-60134 JSONTXT 2 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T287 0-236 Sentence denotes TIGIT receptor, present in T and NK cells, can bind to dendritic cell CD155 receptors and induce an increased expression of IL-10 and reduce IL-12, in addition to inhibiting T cell activation and blocking cytotoxicity of NK cells (196).
T288 237-378 Sentence denotes The use of specific blockers for these receptors, such as anti-PD1 and anti-TIGIT, has helped in the recovery of the function of these cells.
T289 379-580 Sentence denotes Therefore, it is logical to assume that specific NKG2A blockers could be an important tool to assist in the treatment of SARS-CoV-2 infections, restoring the functionality of cytotoxic cells (10, 195).