Id |
Subject |
Object |
Predicate |
Lexical cue |
T228 |
0-175 |
Sentence |
denotes |
Concerning monocytes, COVID-19 patients have shown an abundant circulation of CD14+ CD16+ cells, with a sharper increase in patients who developed severe respiratory syndrome. |
T229 |
176-371 |
Sentence |
denotes |
This subtype of monocytes can over-secrete TNF-α, IL-1β, and IL-6 and expand quickly in systemic infections, implying that they must play an important role in the rapid defense against pathogens. |
T230 |
372-506 |
Sentence |
denotes |
Controversially, these cells are the main producers of IL-10, which makes their exact function in immune responses elusive (170, 171). |
T231 |
507-723 |
Sentence |
denotes |
Additionally, Dutertre et al. (172) demonstrated that CD14+ CD16+ monocytes are responsible for TNF overproduction in HIV infections and might be considered the major actor in immune hyperactivation in disease (172). |