PMC:7652766 / 14890-15601 JSONTXT 2 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T82 0-141 Sentence denotes Therefore, CoVs need to elicit exogenous proteases to perform modifications of their binding receptors necessary for the connection to occur.
T83 142-370 Sentence denotes SARS-CoV-2 has its own furin-like proteases, which play a role in these changes, providing it with an evolutionary advantage in relation to other coronaviruses and improving the process of cell infection and viral dissemination.
T84 371-496 Sentence denotes Concerning exogenous proteins, SARS-CoV-2 can also use host proteins to prepare its S glycoprotein for receptor binding (49).
T85 497-711 Sentence denotes Hoffman et al. (7) demonstrated in vitro that strains of the virus isolated from COVID-19 patients can use both the host protease transmembrane serine protease 2 (TMPRSS2) and cathepsins B/L to prime the S protein.