PMC:7650537 / 138-1551 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T3 0-250 Sentence denotes Kinetics of neutralizing antibodies and immunoglobulin G (IgG) against the nucleo (N) or spike (S) proteins of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) were studied in patients up to 165 days after PCR diagnosis of infection.
T4 251-374 Sentence denotes Two immunoassays were selected out of eight IgG or total antibody tests by comparing their specificities and sensitivities.
T5 375-508 Sentence denotes Sensitivities were calculated with convalescent sera from 26 PCR-confirmed cases, of which 76.9% had neutralizing antibodies (>1:10).
T6 509-653 Sentence denotes Stored sera collected during the summer 2018 (N = 50) and winter seasons 2018/2019 (N = 50) were included to demonstrate the test specificities.
T7 654-812 Sentence denotes IgG kinetics, avidities, and virus-neutralizing capacities were recorded over up to 165 days in eleven patients and five individuals from routine diagnostics.
T8 813-936 Sentence denotes Sensitivities, specificities, and diagnostic accuracies ranged between 80.8–96.3%, 96.0–100%, and 93.7–99.2%, respectively.
T9 937-1022 Sentence denotes Nearly all results were confirmed with two different SARS-CoV-2-specific immunoblots.
T10 1023-1154 Sentence denotes Six (54.4%) patients exhibited stable N-specific IgG indices over 120 days and longer; three of them developed IgG of high avidity.
T11 1155-1265 Sentence denotes The S-specific IgG response was stable in ten (91.0%) patients, and eight (72.7%) had neutralizing antibodies.
T12 1266-1413 Sentence denotes However, the titers were relatively low, suggesting that sustained humoral immunity is uncertain, especially after outpatient SARS-CoV-2 infection.