Id |
Subject |
Object |
Predicate |
Lexical cue |
T3 |
0-250 |
Sentence |
denotes |
Kinetics of neutralizing antibodies and immunoglobulin G (IgG) against the nucleo (N) or spike (S) proteins of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) were studied in patients up to 165 days after PCR diagnosis of infection. |
T4 |
251-374 |
Sentence |
denotes |
Two immunoassays were selected out of eight IgG or total antibody tests by comparing their specificities and sensitivities. |
T5 |
375-508 |
Sentence |
denotes |
Sensitivities were calculated with convalescent sera from 26 PCR-confirmed cases, of which 76.9% had neutralizing antibodies (>1:10). |
T6 |
509-653 |
Sentence |
denotes |
Stored sera collected during the summer 2018 (N = 50) and winter seasons 2018/2019 (N = 50) were included to demonstrate the test specificities. |
T7 |
654-812 |
Sentence |
denotes |
IgG kinetics, avidities, and virus-neutralizing capacities were recorded over up to 165 days in eleven patients and five individuals from routine diagnostics. |
T8 |
813-936 |
Sentence |
denotes |
Sensitivities, specificities, and diagnostic accuracies ranged between 80.8–96.3%, 96.0–100%, and 93.7–99.2%, respectively. |
T9 |
937-1022 |
Sentence |
denotes |
Nearly all results were confirmed with two different SARS-CoV-2-specific immunoblots. |
T10 |
1023-1154 |
Sentence |
denotes |
Six (54.4%) patients exhibited stable N-specific IgG indices over 120 days and longer; three of them developed IgG of high avidity. |
T11 |
1155-1265 |
Sentence |
denotes |
The S-specific IgG response was stable in ten (91.0%) patients, and eight (72.7%) had neutralizing antibodies. |
T12 |
1266-1413 |
Sentence |
denotes |
However, the titers were relatively low, suggesting that sustained humoral immunity is uncertain, especially after outpatient SARS-CoV-2 infection. |