Id |
Subject |
Object |
Predicate |
Lexical cue |
T377 |
358-532 |
Sentence |
denotes |
Vitamin D receptor found in, e.g., monocytes, macrophages, and DCs; ↑ differentiation of monocytes to macrophages; calcitriol ↑ movement and phagocytic ability of macrophages |
T378 |
533-675 |
Sentence |
denotes |
Regulates antimicrobial protein expression (cathelicidin and defensin), which directly kill pathogens, especially bacteria; ↓ IFN-γ production |
T379 |
676-883 |
Sentence |
denotes |
↑ The oxidative burst potential of macrophages; increases superoxide synthesis; reduces the expression of pro-inflammatory cytokines and increases the expression of anti-inflammatory cytokines by macrophages |
T380 |
884-1268 |
Sentence |
denotes |
Homing of T cells to the skin; ↓ T-cell proliferation; inhibitory effects mainly in adaptive immunity (e.g., Th1-cell activity); stimulatory effects in innate immunity; ↓ the effector functions of T helper cells and cytotoxic T cells; ↑ the production of Tregs; inhibitory effect on the differentiation and maturation of the antigen-presenting DCs, and helps program DCs for tolerance |
T381 |
1269-1301 |
Sentence |
denotes |
↓ Antibody production by B cells |