| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T131 |
0-175 |
Sentence |
denotes |
Leptin is an adipocyte-derived hormone with an important role in the central control of energy metabolism and with many pleiotropic effects in different physiological systems. |
| T132 |
176-315 |
Sentence |
denotes |
One of these is the regulatory role between energy metabolism and the immune system, being a pillar in the new concept of immunometabolism. |
| T133 |
316-426 |
Sentence |
denotes |
Leptin receptor, expressed overall in the immune system, acts in both innate and adaptive immune system cells. |
| T134 |
427-516 |
Sentence |
denotes |
As an adipokine, leptin is responsible for the inflammatory state found in overnutrition. |
| T135 |
517-613 |
Sentence |
denotes |
Moreover, in undernutrition status, it plays as crucial mediator of the immunosuppressive state. |
