PMC:7646269 / 3376-5336 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T40 0-132 Sentence denotes A total of seven patients with COVID‐19 who had one or more positive respiratory cultures for Aspergillus fumigatus were identified.
T41 133-217 Sentence denotes According to the AspICU algorithm, 7 four patients were classified as putative IPA.
T42 218-515 Sentence denotes None of the patients had European Organization for Research and Treatment of Cancer/ Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) host factors, including neutropenia and prolonged use of corticosteroids.
T43 516-618 Sentence denotes Only one patient had a pre‐existing lung disease (chronic obstructive pulmonary disease in Patient 1).
T44 619-933 Sentence denotes All four patients had compatible signs (fever refractory to at least 3 days of appropriate therapy or worsening respiratory insufficiency despite appropriate antibiotic therapy and ventilatory support), host factor (glucocorticoid treatment with prednisone equivalent > 20 mg/d) and abnormal radiographic findings.
T45 934-1148 Sentence denotes Radiographic abnormalities included worsening infiltrates (Patient 1), opacities with dense consolidations (Patient 2), cavitary pneumonia (Patient 3) and diffuse interstitial and patchy hazy opacities (Patient 4).
T46 1149-1258 Sentence denotes The remaining three patients were classified as having colonisation as they lacked compatible clinical signs.
T47 1259-1349 Sentence denotes For those three patients, subsequent clinical deterioration was explained by other causes.
T48 1350-1430 Sentence denotes Clinical characteristics of the patients with putative IPA are shown in Table 1.
T49 1431-1459 Sentence denotes The median age was 79 years.
T50 1460-1594 Sentence denotes All experienced worsening respiratory status leading to invasive mechanical ventilation before the isolation of Aspergillus fumigatus.
T51 1595-1671 Sentence denotes The patients had been mechanically ventilated for a mean of 6.8 days (range:
T52 1672-1712 Sentence denotes 1‐14 days) before Aspergillus isolation.
T53 1713-1818 Sentence denotes At Aspergillus isolation, fever and leukocytosis were present in one and all four patients, respectively.
T54 1819-1891 Sentence denotes Serum galactomannan level was positive for only one patient (Patient 2).
T55 1892-1960 Sentence denotes All patients received concomitant broad‐spectrum antibiotic therapy.