| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T336 |
234-331 |
Sentence |
denotes |
Accordingly, we speculate that PDCoV infection successfully activated autophagy in IPEC-J2 cells. |
| T337 |
332-500 |
Sentence |
denotes |
Our speculation was in agreement with a recent research which revealed that PDCoV infection triggered autophagy in LLC-PK1 cells,71 despite using a different cell line. |
| T338 |
501-739 |
Sentence |
denotes |
Undoubtedly, further studies are definitely needed to confirm the autophagy induced by PDCoV infection, to analyze the impact of autophagy on viral replication and to explore the underlying molecular mechanisms of PDCoV-induced autophagy. |
| T339 |
740-914 |
Sentence |
denotes |
It should be noted that the PI3K-AKT-mTOR signaling pathway also plays an important role in many physiological and pathological conditions,69 except for regulating autophagy. |
| T340 |
915-1145 |
Sentence |
denotes |
Finally, we sought to uncover the hidden interaction networks among the DEPs using STRING analysis, and discovered three major functional networks consisting of the RIG-I-like receptor, PDK1-AKT2 and cell cycle signaling pathways. |
| T341 |
1146-1343 |
Sentence |
denotes |
These findings are in accordance with the results of KEGG pathway analysis, thus further consolidating the credibility of these putative signaling pathways involved in PDCoV-infected IPEC-J2 cells. |
