Id |
Subject |
Object |
Predicate |
Lexical cue |
T28 |
98-226 |
Sentence |
denotes |
ACE2 (Angiotensin converting enzyme 2) has been reported to be a central component mediating the viral entry into the host cell. |
T29 |
227-359 |
Sentence |
denotes |
ACE2 is expressed in gastrointestinal tract, endocrine tissues, kidneys, liver/gall bladder, testis and to smaller extents in lungs. |
T30 |
360-556 |
Sentence |
denotes |
The Receptor Binding Domain of spike proteins induces conformational changes in ACE2 receptors, which further dissociates the S1 subunit of the spike and hence initiates host cell membrane fusion. |
T31 |
557-615 |
Sentence |
denotes |
Therefore, ACE2 might play a vital role in drug designing. |