| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T218 |
0-112 |
Sentence |
denotes |
Most natural mutants exhibited similar binding affinities compared to wild-type nCOV-2019 with a few exceptions. |
| T219 |
113-284 |
Sentence |
denotes |
Mutation T478I which is one of the most frequent mutations based on the GISAID database has a binding affinity which is about 6 kcal/mol higher than that of the wild-type. |
| T220 |
285-369 |
Sentence |
denotes |
S494P and A475V showed a slightly lower binding affinity than the wild-type complex. |
| T221 |
370-443 |
Sentence |
denotes |
Other natural mutants showed binding affinities similar to wild-type RBD. |
| T222 |
444-643 |
Sentence |
denotes |
N439K demonstrated a high electrostatic energy which is compensated by large polar solvation energy and this mutant has a total binding energy of −48.27 ± 3.07 kcal/mol which is similar to nCOV-2019. |
