PMC:7605337 / 20813-21677 JSONTXT 6 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T110 0-80 Sentence denotes The RMSD plots for the nCOV-2019 mutants show similar behaviors to nCOV-2019-wt.
T111 81-222 Sentence denotes In most of the variants, the RMSD is very stable during the 300 ns simulation which shows the great tolerance of the interface for mutations.
T112 223-274 Sentence denotes However, a few mutations showed some RMSD variance.
T113 275-362 Sentence denotes In mutation Y489A, the RMSD increases from 1.37 ± 0.21 Å to1.88 ± 0.16 Å after 2000 ns.
T114 363-475 Sentence denotes Mutation Y505A resulted in an increase in RMSD up to 100 ns to a value to 1.98 ± 0.20 Å and decreased afterward.
T115 476-563 Sentence denotes The RMSD for mutation N487A shows an increasing behavior with a value of 2.10 ± 0.23 Å.
T116 564-629 Sentence denotes Mutations N439K, V483A, and V483F showed a stable RMSD of ∼1.5 Å.
T117 630-706 Sentence denotes For mutations T478I, G476S, S494P, and A475V, the RMSD increases up to ∼2 Å.
T118 707-809 Sentence denotes These variations in the backbone RMSD show the involvement of these residues in the complex stability.
T119 810-864 Sentence denotes RMSD plots for other mutations are shown in Figure S1.