LitCovid-sentences  

PMC:7601109 / 64196-67092 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T383 0-244 Sentence denotes Mitchell and colleagues examined changes in microvascular blood volume, microvascular flow velocity, and microvascular blood flow in the quadriceps muscle following treatment with 15 g of amino acids in young and old subjects (20–70 years old).
T384 245-381 Sentence denotes They detected improvements in all the 3 parameters only in young groups, and those effects were associated with proper insulin activity.
T385 382-550 Sentence denotes Thus, the authors suggested that refeeding effects on muscular blood supply may be hindered by dysfunctions in postprandial circulation and glucose dysregulation [157].
T386 551-751 Sentence denotes Bee products such as bee pollen and propolis have a potential to boost microcirculation and correct pathologies that contribute to vascular dysfunction such as hyperglycemia and dyslipidemia [36,155].
T387 752-936 Sentence denotes In this context, CAPE, one of the basic constituents of propolis, was reported to combat vascular damages by counteracting the proliferative activity of platelet-derived growth factor.
T388 937-1289 Sentence denotes The molecular mechanism involved inducing cell-cycle arrest in VSMCs via activation of p38mitogen-activated protein kinase (MAPK), which was associated with accumulation of hypoxia-inducible factor (HIF)-1α—mainly due to inhibition of HIF prolylhydroxylase, a key contributor to proteasomal degradation of HIF-1α—and subsequent induction of HO-1 [155].
T389 1290-1720 Sentence denotes In the same regard, supplementing rats undergoing capillary regression (resulting from two weeks of hind limb unloading) in the soleus muscle with two daily intragastric doses of propolis for two weeks restored capillary number, capillary structure, capillary volume, and capillary to muscle fiber ratio through a mechanism that involves inhibition of anti-angiogenic factors and activation of pro-angiogenic factors (e.g., VEGF).
T390 1721-1962 Sentence denotes The relative muscle-to-body weight in treated animals was higher than in the unloaded control animals, and the number of TUNEL-positive apoptotic endothelial cells in the soleus muscle was similar to that in the normal control animals [110].
T391 1963-2129 Sentence denotes Likewise, bee pollen (both neat and processed) increased blood vessels in the gastrocnemius muscle of rats undergoing muscle injury because of vigorous exercise [90].
T392 2130-2219 Sentence denotes Treating C2C12 myoblasts with propolis ethanolic extract increased VEGF production [108].
T393 2220-2383 Sentence denotes VEGF is a pro-angiogenic factor that contributes to angiogenesis by recruiting endothelial cells and promoting their differentiation to form new vascular networks.
T394 2384-2489 Sentence denotes VEGF protects skeletal muscle undergoing unloading against the progression of capillary regression [110].
T395 2490-2636 Sentence denotes Its expression in skeletal muscle and associated angiogenic response increase following exercise due to change in the activity of HIF-1α and AMPK.
T396 2637-2743 Sentence denotes It promotes the generation of ATP following mitochondrial biogenesis in order to meet oxygen demand [158].
T397 2744-2896 Sentence denotes Altogether, these reports signify that bee products and endurance exercise share common mechanisms to produce their vitality effects in skeletal muscle.