| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T252 |
0-76 |
Sentence |
denotes |
Skeletal muscle is the main tissue that utilizes insulin for glucose uptake. |
| T253 |
77-375 |
Sentence |
denotes |
Insulin regulates mitochondrial oxidative phosphorylation of proteins in human skeletal muscle and contributes to calcium mobilization from the sarcoplasmic-endoplasmic reticulum to mitochondria to stimulate the translocation of glucose transporter 4 (GLUT4) to the cell surface for glucose uptake. |
| T254 |
376-567 |
Sentence |
denotes |
This process improves muscle protein synthesis in healthy people when the delivery of amino acids to skeletal muscle is increased, eventually leading to increased muscular mass [124,125,126]. |
| T255 |
568-653 |
Sentence |
denotes |
Insulin resistance and glucose intolerance increase with old age evoking muscle loss. |
| T256 |
654-827 |
Sentence |
denotes |
In this respect, hypoglycemic agents such as metformin can improve skeletal muscle metabolism via activation of adenosine monophosphate activated protein kinase (AMPK) [21]. |
