PMC:7601109 / 26764-28448 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T176 0-298 Sentence denotes Though few animal models were used to examine the effect of bee products on sarcopenia, findings indicate that royal jelly, propolis, and bee pollen can induce both structural and symptomatic improvements and reduce behavioral dysfunctions associated with sarcopenia in rodents (Figure 1, Panel C).
T177 299-728 Sentence denotes Both crude and protease-treated royal jelly (pRJ) significantly delayed age-related impairment of motor functions in d-galactose induced mouse model of aging [95], naturally aged sarcopenic mice [96], and in genetically heterogeneous head tilt (HET) mice—which exhibit vestibular dysfunction, imbalanced position, and inability to swim—by improving performance on grip strength, wire hang, horizontal bar, and rotarod tests [97].
T178 729-925 Sentence denotes Similarly, royal jelly improved physical performance in aged rodents—it significantly increased the number of crossings and swimming speed and prolonged swimming distance in water maze [96,98,99].
T179 926-1342 Sentence denotes In addition, royal jelly decreased lipid accumulation in skeletal muscle [100], positively improved the size of muscle fibers, lowered age-related reduction of skeletal muscle weight [95,96,97,100], increased the differentiation and proliferation rate of muscle satellite cell, improved the regenerative capacity of injured muscle, and suppressed catabolic genes in aged mice with sarcopenia and in HET mice [96,97].
T180 1343-1477 Sentence denotes The muscle mass-accelerating effects of 10-HDA, a key fatty acid in royal jelly, were more pronounced in male animals than in females.
T181 1478-1559 Sentence denotes However, 10-HDA mitigated the accumulation of adipose tissue in female mice [54].
T182 1560-1684 Sentence denotes It is note-worthy that pRJ had no effect on muscle strength and physical performance in humans aged 70 years and above [59].