Id |
Subject |
Object |
Predicate |
Lexical cue |
T787 |
0-65 |
Sentence |
denotes |
Therapy Type Mechanism No. of Interventional Clinical Trials b |
T788 |
66-145 |
Sentence |
denotes |
Tocilizumab(Actemra) Humanized monoclonal antibody IL-6 receptor blocker ~41 |
T789 |
146-209 |
Sentence |
denotes |
Ruxolitinib(Jakafi) Small molecule JAK 1 and 2 inhibitor ~15 |
T790 |
210-318 |
Sentence |
denotes |
Colchicine(Colcrys) Small molecule Inhibition of NLRP3 inflammasome and of microtubule polymerization ~15 |
T791 |
319-415 |
Sentence |
denotes |
Anakinra(Kineret) Recombinant non-glycosylated human polypeptide IL-1 receptor antagonist ~13 |
T792 |
416-590 |
Sentence |
denotes |
Methylprednisolone (DEPOMedrol) Small molecule Intracellular receptor-mediated gene expression & suppression of migration of polymorphonuclear leukocytes, among others ~13 |
T793 |
591-656 |
Sentence |
denotes |
Baricitinib(Olumiant) Small molecule JAK 1 and 2 inhibitor ~12 |
T794 |
657-730 |
Sentence |
denotes |
Sarilumab(Kevzara) Human monoclonal antibody IL-6 receptor blocker ~10 |
T795 |
731-973 |
Sentence |
denotes |
Dexamethasone(Decadron, Active Injection D) Small molecule Stimulation of glucocorticoid receptors, suppression of neutrophil migration, suppression of inflammatory mediators production, and reversal of increased capillary permeability ~10 |
T796 |
974-1037 |
Sentence |
denotes |
Sirolimus(Rapamune) Small molecule mTOR pathway inhibitor ~4 |
T797 |
1038-1106 |
Sentence |
denotes |
Mavrilimumab Human monoclonal antibody GM-CSF receptor blocker ~4 |
T798 |
1107-1171 |
Sentence |
denotes |
Siltuximab(Sylvant) Chimeric monoclonal antibody Anti-IL-6 ~2 |
T799 |
1172-1234 |
Sentence |
denotes |
Canakinumab(Ilaris) Human monoclonal antibody Anti-IL-1β ~2 |