| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T744 |
0-125 |
Sentence |
denotes |
Figure 5 (A) Chemical structure of EIDD-2801, an isopropyl ester prodrug of ribonucleoside analog of β-D-N4-hydroxycytidine. |
| T745 |
126-225 |
Sentence |
denotes |
EIDD-2801 is an orally bioavailable nucleoside derivative that is under development for SARS-CoV-2. |
| T746 |
226-617 |
Sentence |
denotes |
Also depicted is its activation to the corresponding tri-phosphorylated form which exhibits a broad-spectrum antiviral activity against various RNA viruses, including coronaviruses with resistance mutations to remdesivir. (B) The active form exists in two forms: the oxime form which mimics uridine and pairs with adenosine, while the other tautomer mimics cytidine and pairs with guanosine. |
| T747 |
618-673 |
Sentence |
denotes |
The drug eventually leads to a viral error catastrophe. |
