| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T337 |
0-113 |
Sentence |
denotes |
In one hand, indomethacin is a synthetic, small molecule of N-benzoyl-indole-3-acetic acid derivative (Figure 7). |
| T338 |
114-147 |
Sentence |
denotes |
It was first approved by the U.S. |
| T339 |
148-177 |
Sentence |
denotes |
FDA in 1984 for use as NSAID. |
| T340 |
178-233 |
Sentence |
denotes |
It also possesses analgesic and antipyretic properties. |
| T341 |
234-277 |
Sentence |
denotes |
It is used for acute mild to moderate pain. |
| T342 |
278-409 |
Sentence |
denotes |
It is also used for ankylosing spondylitis, bursitis, tendonitis, osteoarthritis, and rheumatoid arthritis, among other conditions. |
| T343 |
410-563 |
Sentence |
denotes |
The known mechanism is the reversible inhibition of cyclooxygenase-1 and 2 enzymes, which leads to decreased formation of prostaglandin precursors [142]. |
| T344 |
564-815 |
Sentence |
denotes |
Orally administered indomethacin is being evaluated in combination with hydroxychloroquine and azithromycin in an open-label, single-arm, phase 2 study to determine its efficacy and safety in subjects with mild COVID-19 symptoms (NCT04344457; n = 80). |
