| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T521 |
0-89 |
Sentence |
denotes |
As mentioned before, ssNMR can provide information about membranes and membrane proteins. |
| T522 |
90-522 |
Sentence |
denotes |
For this reason, ssNMR can be used to detect interactions of ligands with receptors embedded to the membrane which enables the mapping of binding site of a receptor by utilizing CP-MAS (cross-polarization magic-angle spinning) NMR and site specific mutagenesis [355]. ssNMR can provide the conformation of ligands bound to the receptor which can then be used to optimize future drug in terms of better affinity and efficiency [355]. |
| T523 |
523-680 |
Sentence |
denotes |
Since ssNMR is also applicable to amyloid research, it can be used for probing polypeptide structures of amyloid and intermolecular contacts between fibrils. |
| T524 |
681-796 |
Sentence |
denotes |
The potential is for the design a drug that will inhibit the process of aggregation of proteins and peptides [355]. |
| T525 |
797-1007 |
Sentence |
denotes |
Lastly, since ssNMR gains insight into physical properties of a chemical compound it can be used for control of the process of formulation and processing of a drug to help assess the purity of a compound [358]. |
