| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T315 |
0-191 |
Sentence |
denotes |
Saturation Transfer Difference (STD) NMR depends on the Nuclear Overhauser Effect (NOE), which is often used to enhance the sensitivity of less sensitive nuclei such as 13C and 15N [256,257]. |
| T316 |
192-321 |
Sentence |
denotes |
This increase in sensitivity is possible because of dipolar coupling (i.e., through space interactions of separate nuclei) [257]. |
| T317 |
322-668 |
Sentence |
denotes |
The increase in sensitivity is actually brought about by applying a long, low power radiofrequency pulse that selectively saturates the magnetization [256] of a specific chemical group (i.e., the methyl groups on a protein), which is then given time to transfer to another chemical group via the NOE dipolar coupling within a few angstroms [258]. |
| T318 |
669-829 |
Sentence |
denotes |
The transfer in magnetization is easily visualized on a NMR spectrum that takes the differences in the signal intensities from before and after the irradiation. |
| T319 |
830-976 |
Sentence |
denotes |
This new spectrum is called a “difference spectrum”, and it reveals what chemical groups interact with the irradiated signal [259] (see Figure 8). |
