| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T676 |
0-181 |
Sentence |
denotes |
Another program that can utilize CSP called Smoothed Automatic Mapping of Protein from Listed Extremes (SAMPLEX) can help to determine the interaction surface of proteins complexes. |
| T677 |
182-339 |
Sentence |
denotes |
SAMPLEX takes the chemical shifts of the protein of interests in both the free and bound state and corresponding 3D structure of a protein in the free state. |
| T678 |
340-523 |
Sentence |
denotes |
The programs returns a confidence value for each residue to be in a perturbed or unperturbed state (0.05 as being in a perturbed state, −0.05 as remaining in their unperturbed state). |
| T679 |
524-672 |
Sentence |
denotes |
This approach was tested on five examples, one of which was Subtilisin BPN’ (serine protease) complexed with its inhibitor–chymotrypsin inhibitor 2. |
| T680 |
673-811 |
Sentence |
denotes |
The results showed that residue 2, and residues 56–62 of chymotrypsin inhibitor-2 were perturbed and residue 63 was in an ambiguous state. |
| T681 |
812-918 |
Sentence |
denotes |
To compare, the X-ray crystallography data showed residues 50 and 54–61 to be involved in the interaction. |
| T682 |
919-1095 |
Sentence |
denotes |
For subtilisin BPN’ the program predicted residues 33, 97, 99–109, 126-128, 141, 154–156, 167–171 and 218–219 to perturbed and residues 65, 98 and 220 to be in ambiguous state. |
| T683 |
1096-1251 |
Sentence |
denotes |
That information was also confronted with the X-ray crystallography data which shown residues 99–104, 125–128, 154–157, 167, 218–221 to be perturbed [408]. |
