| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T68 |
0-42 |
Sentence |
denotes |
Vitamin A also supports adaptive immunity. |
| T69 |
43-208 |
Sentence |
denotes |
Indeed, retinoids represents physiological modulators of normal B cell growth and differentiation, thus vitamin A deficiency negatively affects B cell function [18]. |
| T70 |
209-317 |
Sentence |
denotes |
Furthermore, animal studies have shown impairment in the antibody response due to vitamin A deficiency [19]. |
| T71 |
318-467 |
Sentence |
denotes |
The production of antibodies may be enhanced by the influence of vitamin A on T helper 2 cells development [22] and antigen-presenting cells [15,23]. |
| T72 |
468-609 |
Sentence |
denotes |
In addition, retinoids induce the differentiation of Tregs and maintain both the stability of Tregs and their immunoregulatory function [24]. |
| T73 |
610-828 |
Sentence |
denotes |
Indeed, retinoids play fundamental roles in cell-mediated immunity, representing an important cofactor in T cell activation [25] and influencing the expression of membrane receptors that mediate T-cell signalling [17]. |
| T74 |
829-996 |
Sentence |
denotes |
Vitamin A supplementation trials conducted in paediatric populations have shown the potential effect to increase T-cell, particularly of the CD4 subpopulation [15,26]. |
