Id |
Subject |
Object |
Predicate |
Lexical cue |
T598 |
0-73 |
Sentence |
denotes |
Table 8 Efficacy of zinc in treating respiratory illnesses in childhood. |
T599 |
74-131 |
Sentence |
denotes |
Study Author Country Study Population Dosage Results |
T600 |
132-320 |
Sentence |
denotes |
Randomized, double-blind, placebo-controlled clinical trial of the efficacy of treatment with zinc or vitamin a in infants and young children with severe acute lower respiratory infection. |
T601 |
322-521 |
Sentence |
denotes |
Mahalanabis et al., 2004 [253] India 153 children hospitalized with severe ALRI 10 mg twice daily for 5 days Significantly reduced duration of fever and very ill status in boys, but not in girls. |
T602 |
522-610 |
Sentence |
denotes |
Efficacy of zinc in the treatment of severe pneumonia in hospitalized children <2 y old. |
T603 |
612-832 |
Sentence |
denotes |
Bose et al., 2006 [254] India 299 children hospitalized with severe pneumonia 20 mg/day during hospital stay No overall effect on the duration of hospitalization or of clinical signs associated with severe infection. |
T604 |
833-991 |
Sentence |
denotes |
A randomized controlled trial of the effect of zinc as adjuvant therapy in children 2–35 months of age with severe or nonsevere pneumonia in Bhaktapur, Nepal. |
T605 |
993-1210 |
Sentence |
denotes |
Valentiner-Branth et al., 2010 [255] Nepal Over 2000 children with pneumonia 10 mg if aged 2–11 months, 20 mg if aged > or =12 months, for 14 days No decrease in risk of treatment failure nor accelerated recovery. |
T606 |
1211-1319 |
Sentence |
denotes |
A randomized controlled trial of oral zinc in acute pneumonia in children aged between 2 months and 5 years. |
T607 |
1321-1466 |
Sentence |
denotes |
Ganguly et al., 2011 [256] India 98 children with pneumonia 10 mg/day if <1 year, 20 mg if >1 year of age No improvement in symptom duration. |
T608 |
1467-1549 |
Sentence |
denotes |
The efficacy of zinc supplementation on outcome of children with severe pneumonia. |
T609 |
1550-1610 |
Sentence |
denotes |
A randomized double-blind placebo-controlled clinical trial. |
T610 |
1612-1779 |
Sentence |
denotes |
Valavi et al., 2011[257] Iran 128 children with severe pneumonia 2 mg/kg/day, max 20 mg, for 5 days Shorter time for symptoms resolution and shorter hospital stay. |
T611 |
1780-1863 |
Sentence |
denotes |
Zinc Supplementation in Severe Acute Lower Respiratory Tract Infection in Children: |
T612 |
1864-1915 |
Sentence |
denotes |
A Triple-Blind Randomized Placebo Controlled Trial. |
T613 |
1917-2067 |
Sentence |
denotes |
Bansal et al., 2011 [258] India Children hospitalized with ALRI 20 mg/day for 5 days No decrease in recovery time or in duration of hospital stay. |
T614 |
2068-2152 |
Sentence |
denotes |
Role of zinc in severe pneumonia: a randomized double bind placebo-controlled study. |
T615 |
2154-2305 |
Sentence |
denotes |
Shah et al., 2012 [259] Nepal Children hospitalized for severe pneumonia 20 mg/die for 7 days No effect on clinical recovery from severe pneumonia. |
T616 |
2306-2403 |
Sentence |
denotes |
A randomized controlled trial of zinc as adjuvant therapy for severe pneumonia in young children. |
T617 |
2405-2635 |
Sentence |
denotes |
Basnet et al., 2012 [260] Nepal 610 children with severe pneumonia 10 mg if <11 months, 20 mg/day if >11 months, for 14 days Slightly faster recovery, slightly lower risk of treatment failure but not statistically significant. |
T618 |
2636-2761 |
Sentence |
denotes |
Zinc adjunct therapy reduces case fatality in severe childhood pneumonia: a randomized double-blind placebo-controlled trial. |
T619 |
2763-2974 |
Sentence |
denotes |
Srinivasan et al., 2012 [261] Uganda 352 children with severe pneumonia 20 mg if ≥12 months, 10 mg if <12 months, for 7 days No significant effect on time to resolution of symptoms; decreased mortality rate. |
T620 |
2975-3163 |
Sentence |
denotes |
Efficacy of zinc given as an adjunct in the treatment of severe and very severe pneumonia in hospitalized children 2–24 months of age: a randomized, double-blind, placebo-controlled trial. |
T621 |
3165-3314 |
Sentence |
denotes |
Wadhwa et al., 2013 [262] India 550 children hospitalized with severe pneumonia 20 mg/day during hospital stay No difference in time to recovery. |
T622 |
3315-3425 |
Sentence |
denotes |
Zinc as an adjunct to the treatment of severe pneumonia in Ecuadorian children: a randomized controlled trial. |
T623 |
3427-3701 |
Sentence |
denotes |
Sempertegui et al., 2014 [263] Ecuador 450 children hospitalized with pneumonia 20 mg/day during hospital stay No effect on time to pneumonia resolution nor in treatment failure rate.Higher basal zinc concentrations associated with faster resolution of chest indrawings. |
T624 |
3702-3766 |
Sentence |
denotes |
Effect of zinc supplementation on infants with severe pneumonia. |
T625 |
3768-3936 |
Sentence |
denotes |
Yuan et al., 2016 [264] China 73 infants hospitalized for pneumonia 10 mg/day if <6 mo; 20 mg/day if >6 moduring hospital stay No improvements on clinical outcomes. |
T626 |
3937-4054 |
Sentence |
denotes |
Zinc as an adjunct therapy in the management of severe pneumonia among Gambian children: randomized controlled trial. |
T627 |
4056-4326 |
Sentence |
denotes |
Howie et al., 2018 [265] Gambia Over 600 children with severe pneumonia 10 mg if <12 mo; 20 mg if > 20 mo, for 7 days No benefit in treatment failure rates or time to recovery from respiratory symptoms; marginal benefit in rapidity of resolution of chest indrawings. |
T628 |
4327-4470 |
Sentence |
denotes |
Zinc supplementation promotes a th1 response and improves clinical symptoms in fewer hours in children with pneumonia younger than 5 years old. |
T629 |
4471-4510 |
Sentence |
denotes |
A randomized controlled clinical trial. |
T630 |
4512-4741 |
Sentence |
denotes |
Acevedo-Murillo et al., 2019 [266] Mexico 103 children hospitalized for pneumonia 10 mg/day if <1 year; 20 mg/day if >1 year during hospital stay Quicker improvement in clinical status, oxygen saturation and respiratory rate. |
T631 |
4742-4797 |
Sentence |
denotes |
Patients’ baseline zinc levels were below normal range. |
T632 |
4798-4923 |
Sentence |
denotes |
A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children. |
T633 |
4925-5090 |
Sentence |
denotes |
Rerksuppaphol et al., 2019 [267] Thailand 64 hospitalized children with ALRI 30 mg/day during hospital stay Faster symptoms resolution and shorter hospital stay. |
T634 |
5091-5137 |
Sentence |
denotes |
ALRI, acute lower respiratory tract infection. |