PMC:7589163 / 91292-96429 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T598 0-73 Sentence denotes Table 8 Efficacy of zinc in treating respiratory illnesses in childhood.
T599 74-131 Sentence denotes Study Author Country Study Population Dosage Results
T600 132-320 Sentence denotes Randomized, double-blind, placebo-controlled clinical trial of the efficacy of treatment with zinc or vitamin a in infants and young children with severe acute lower respiratory infection.
T601 322-521 Sentence denotes Mahalanabis et al., 2004 [253] India 153 children hospitalized with severe ALRI 10 mg twice daily for 5 days Significantly reduced duration of fever and very ill status in boys, but not in girls.
T602 522-610 Sentence denotes Efficacy of zinc in the treatment of severe pneumonia in hospitalized children <2 y old.
T603 612-832 Sentence denotes Bose et al., 2006 [254] India 299 children hospitalized with severe pneumonia 20 mg/day during hospital stay No overall effect on the duration of hospitalization or of clinical signs associated with severe infection.
T604 833-991 Sentence denotes A randomized controlled trial of the effect of zinc as adjuvant therapy in children 2–35 months of age with severe or nonsevere pneumonia in Bhaktapur, Nepal.
T605 993-1210 Sentence denotes Valentiner-Branth et al., 2010 [255] Nepal Over 2000 children with pneumonia 10 mg if aged 2–11 months, 20 mg if aged > or =12 months, for 14 days No decrease in risk of treatment failure nor accelerated recovery.
T606 1211-1319 Sentence denotes A randomized controlled trial of oral zinc in acute pneumonia in children aged between 2 months and 5 years.
T607 1321-1466 Sentence denotes Ganguly et al., 2011 [256] India 98 children with pneumonia 10 mg/day if <1 year, 20 mg if >1 year of age No improvement in symptom duration.
T608 1467-1549 Sentence denotes The efficacy of zinc supplementation on outcome of children with severe pneumonia.
T609 1550-1610 Sentence denotes A randomized double-blind placebo-controlled clinical trial.
T610 1612-1779 Sentence denotes Valavi et al., 2011[257] Iran 128 children with severe pneumonia 2 mg/kg/day, max 20 mg, for 5 days Shorter time for symptoms resolution and shorter hospital stay.
T611 1780-1863 Sentence denotes Zinc Supplementation in Severe Acute Lower Respiratory Tract Infection in Children:
T612 1864-1915 Sentence denotes A Triple-Blind Randomized Placebo Controlled Trial.
T613 1917-2067 Sentence denotes Bansal et al., 2011 [258] India Children hospitalized with ALRI 20 mg/day for 5 days No decrease in recovery time or in duration of hospital stay.
T614 2068-2152 Sentence denotes Role of zinc in severe pneumonia: a randomized double bind placebo-controlled study.
T615 2154-2305 Sentence denotes Shah et al., 2012 [259] Nepal Children hospitalized for severe pneumonia 20 mg/die for 7 days No effect on clinical recovery from severe pneumonia.
T616 2306-2403 Sentence denotes A randomized controlled trial of zinc as adjuvant therapy for severe pneumonia in young children.
T617 2405-2635 Sentence denotes Basnet et al., 2012 [260] Nepal 610 children with severe pneumonia 10 mg if <11 months, 20 mg/day if >11 months, for 14 days Slightly faster recovery, slightly lower risk of treatment failure but not statistically significant.
T618 2636-2761 Sentence denotes Zinc adjunct therapy reduces case fatality in severe childhood pneumonia: a randomized double-blind placebo-controlled trial.
T619 2763-2974 Sentence denotes Srinivasan et al., 2012 [261] Uganda 352 children with severe pneumonia 20 mg if ≥12 months, 10 mg if <12 months, for 7 days No significant effect on time to resolution of symptoms; decreased mortality rate.
T620 2975-3163 Sentence denotes Efficacy of zinc given as an adjunct in the treatment of severe and very severe pneumonia in hospitalized children 2–24 months of age: a randomized, double-blind, placebo-controlled trial.
T621 3165-3314 Sentence denotes Wadhwa et al., 2013 [262] India 550 children hospitalized with severe pneumonia 20 mg/day during hospital stay No difference in time to recovery.
T622 3315-3425 Sentence denotes Zinc as an adjunct to the treatment of severe pneumonia in Ecuadorian children: a randomized controlled trial.
T623 3427-3701 Sentence denotes Sempertegui et al., 2014 [263] Ecuador 450 children hospitalized with pneumonia 20 mg/day during hospital stay No effect on time to pneumonia resolution nor in treatment failure rate.Higher basal zinc concentrations associated with faster resolution of chest indrawings.
T624 3702-3766 Sentence denotes Effect of zinc supplementation on infants with severe pneumonia.
T625 3768-3936 Sentence denotes Yuan et al., 2016 [264] China 73 infants hospitalized for pneumonia 10 mg/day if <6 mo; 20 mg/day if >6 moduring hospital stay No improvements on clinical outcomes.
T626 3937-4054 Sentence denotes Zinc as an adjunct therapy in the management of severe pneumonia among Gambian children: randomized controlled trial.
T627 4056-4326 Sentence denotes Howie et al., 2018 [265] Gambia Over 600 children with severe pneumonia 10 mg if <12 mo; 20 mg if > 20 mo, for 7 days No benefit in treatment failure rates or time to recovery from respiratory symptoms; marginal benefit in rapidity of resolution of chest indrawings.
T628 4327-4470 Sentence denotes Zinc supplementation promotes a th1 response and improves clinical symptoms in fewer hours in children with pneumonia younger than 5 years old.
T629 4471-4510 Sentence denotes A randomized controlled clinical trial.
T630 4512-4741 Sentence denotes Acevedo-Murillo et al., 2019 [266] Mexico 103 children hospitalized for pneumonia 10 mg/day if <1 year; 20 mg/day if >1 year during hospital stay Quicker improvement in clinical status, oxygen saturation and respiratory rate.
T631 4742-4797 Sentence denotes Patients’ baseline zinc levels were below normal range.
T632 4798-4923 Sentence denotes A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
T633 4925-5090 Sentence denotes Rerksuppaphol et al., 2019 [267] Thailand 64 hospitalized children with ALRI 30 mg/day during hospital stay Faster symptoms resolution and shorter hospital stay.
T634 5091-5137 Sentence denotes ALRI, acute lower respiratory tract infection.