PMC:7589163 / 66110-69392 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T411 0-76 Sentence denotes Table 2 Main studies on vitamin A supplementation against viral infections.
T412 77-141 Sentence denotes Study Author Study Population Micronutrient (Dosage) Results
T413 142-194 Sentence denotes Vitamin A and respiratory syncytial virus infection.
T414 195-233 Sentence denotes Serum level and supplementation trial.
T415 235-441 Sentence denotes Kyran P 1996 [37] ChildrenRCT Vitamin A (100,000 UI) Lower mean vitamin A levels in RSV-infected children than in healthy control (p < 0.05).No significant difference in improvement in clinical outcomes.
T416 442-559 Sentence denotes Treatment of respiratory syncytial virus infection with vitamin A: a randomized placebo-controlled trial in Santiago.
T417 561-746 Sentence denotes Dowell SF 1996 [38] ChildrenRCT Vitamin A (50,000 to 200,000 UI, dosed according to age) More rapid resolution of tachypnea (p = 0.01).Shorter duration of hospitalization (p = 0.09).
T418 747-863 Sentence denotes Vitamin A therapy for children with respiratory syncytial virus infection: a multicenter trial in the United States.
T419 865-1147 Sentence denotes Bresee JS 1996 [39] ChildrenRCT Vitamin A (50,000 to 200,000 UI, dosed according to age) Not significantly different in the number of days during which supplemental oxygen was required.Not significant difference in the number of days required to achieve normal respiratory rates.
T420 1148-1259 Sentence denotes Vitamin A supplements and diarrheal and respiratory tract infections among children in Dar es Salaam, Tanzania.
T421 1261-1447 Sentence denotes Fawzi WW 2000 [40] Children RCT Vitamin A (100,000 to 200,000 UI, dosed according to age) Significantly higher risk of cough and rapid respiratory rate (p = 0.004) in treatment group.
T422 1448-1546 Sentence denotes Vitamin A for preventing acute lowe respiratory tract infections in children up to 7 years of age.
T423 1548-1555 Sentence denotes Chen H.
T424 1556-1931 Sentence denotes 2008 [43] Children from areas or with conditions correlated with a status of vitamin A deficiency.10 RCTs Vitamin A (6 studies were large-dose trials (100,000 UI o 200,000 UI) 4 studies were low-dose trials (5000 UI daily or 10,000 UI weekly or 45,000 UI every 2 months) No significant effect on the incidence or prevalence of ALRI symptoms with vitamin A supplementation.
T425 1932-2061 Sentence denotes Vitamin A supplementation for prophylaxis or therapy in childhood pneumonia: a systematic review of randomized controlled trials.
T426 2063-2163 Sentence denotes Mathew JL 2010 [42] Children20 RCTs Vitamin A (prophylaxis trial: >100,000 UI; therapeutic trials:
T427 2164-2259 Sentence denotes 100,000 UI o 200,000 UI) Neither prophylactic nor therapeutic benefit for childhood pneumonia.
T428 2260-2397 Sentence denotes Vitamin A supplementation every 6 months with retinol in 1 million pre-school children in north India: DEVTA, a cluster-randomized trial.
T429 2399-2503 Sentence denotes Awasthi S 2013 [32] ChildrenRCT Vitamin A (200,000 UI 6-monthly) Not significant mortality reduction.
T430 2504-2613 Sentence denotes Vitamin A supplementation for preventing morbidity and mortality in children from 6 months to 5 years of age.
T431 2615-2739 Sentence denotes Imdad A 2017 [33] Children42 RCTs Vitamin A (large-dose trials: range of 50,000 UI to 200,000 UI, except for five studies:
T432 2740-3123 Sentence denotes 3866 UI 3 times a week, 8333 UI once a week, 10,000 UI weekly and 250,000 UI 2 times a week) 12% reduction in all-cause mortality (RR 0.88 95% CI 0.83 to 0.93) in the interevention group.Not significant difference in ALRI-mortality.Not effect for vitamin A supplementation on ALRI incidence (only 2 trials reported ALRI prevalence, suggesting benefit for vitamin A supplementation).
T433 3124-3282 Sentence denotes ALRI, acute lower respiratory tract infection; CI, confidence interval; RCT, randomized controlled trial; RR, relative risk; RSV, respiratory syncytial virus.