| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T281 |
0-138 |
Sentence |
denotes |
Linoleic acid (18:2n-6) and α-linolenic acid (18:3n-3) are essential fatty acids (EFAs), meaning that they must be obtained from the diet. |
| T282 |
139-245 |
Sentence |
denotes |
Indeed, they are synthesized by plants and cannot be synthesized sufficiently by the human organism [190]. |
| T283 |
246-438 |
Sentence |
denotes |
However, animals can metabolize α-linolenic acid by further desaturation and elongation to yield eicosapentaenoic acid (20:5n-3; known as EPA) and docosahexaenoic acid (22:6n-3; known as DHA). |
| T284 |
439-601 |
Sentence |
denotes |
It is important to note that the same enzymes are employed by omega-6 fatty acids for their metabolic pathways, which leads to the production of arachidonic acid. |
| T285 |
602-711 |
Sentence |
denotes |
This means that α-linolenic acid is a competitive inhibitor of linoleic acid metabolism and vice versa [191]. |
| T286 |
712-847 |
Sentence |
denotes |
However, it has been demonstrated that the conversion to EPA and DHA is generally poor in humans, with reported rates of less than 15%. |
| T287 |
848-910 |
Sentence |
denotes |
Therefore, these fatty acids must be supplied with food [192]. |
| T288 |
911-1016 |
Sentence |
denotes |
Alfa-linolenic acid is present in plant oils, DHA and EPA are present in fish, fish oils, and krill oils. |
