LitCovid-sentences  

PMC:7574920 / 58711-62577 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T422 0-15 Sentence denotes Acknowledgments
T423 16-27 Sentence denotes We thank V.
T424 28-41 Sentence denotes Pelechano, X.
T425 42-53 Sentence denotes Yin, and V.
T426 54-115 Sentence denotes Lohmann for helpful discussions and sharing unpublished work.
T427 116-127 Sentence denotes We thank U.
T428 128-334 Sentence denotes Merle for providing specimens and the diagnostic laboratory team at Heidelberg University Hospital for providing RNA samples isolated from pharyngeal swabs collected from patients being tested for COVID-19.
T429 335-346 Sentence denotes We thank V.
T430 347-366 Sentence denotes Sonntag-Buck, A.-M.
T431 367-377 Sentence denotes Heuser, I.
T432 378-388 Sentence denotes Ambiel, S.
T433 389-399 Sentence denotes Winter, T.
T434 400-414 Sentence denotes Müller, and S.
T435 415-454 Sentence denotes Horner for excellent technical support.
T436 455-466 Sentence denotes We thank A.
T437 467-484 Sentence denotes Uvarovskii and S.
T438 485-524 Sentence denotes Ovchinnikova for IT-related help and S.
T439 525-538 Sentence denotes Kreger and U.
T440 539-575 Sentence denotes Jäkle for additional technical help.
T441 576-668 Sentence denotes Funding: V.L.D.T., A.F., and P.C. were supported by the Chica and Heinz Schaller foundation.
T442 669-742 Sentence denotes M.K. was supported by the Deutsche Forschungsgemeinschaft (DFG; grant no.
T443 743-755 Sentence denotes KN498/11-1).
T444 756-812 Sentence denotes S.B. was supported by the Heisenberg program of the DFG.
T445 813-901 Sentence denotes Author contributions: V.L.D.T., H.-G.K., M.K., and S.A. conceived and planned the study.
T446 902-1062 Sentence denotes V.L.D.T., M.M., K.B., and M.K. planned and designed the experiments on the RT-LAMP assay and performed them together with Daniel Kirrmaier, A.F., S.K., and P.C.
T447 1063-1144 Sentence denotes V.L.D.T., K.B., and M.K. performed the experiments for the swab–to–RT-LAMP assay.
T448 1145-1232 Sentence denotes K.H. designed the LAMP-sequencing assay and performed it with Daniel Kirrmaier and M.K.
T449 1233-1403 Sentence denotes K.B. performed the RT-qPCR analyses of samples and organized, together with I.B.M., P.S., Dina Khalid, and H.-G.K., provision of the samples by the diagnostic laboratory.
T450 1404-1466 Sentence denotes D.P. and C.G. tested sample handling and logistics strategies.
T451 1467-1536 Sentence denotes V.L.D.T., M.K., M.L.S., and S.B. tested viral inactivation protocols.
T452 1537-1625 Sentence denotes S.A. performed data analysis of the RT-LAMP experiments, together with L.P.M.K. and K.H.
T453 1626-1665 Sentence denotes K.H. analyzed the LAMP-sequencing data.
T454 1666-1709 Sentence denotes V.L.D.T. analyzed the swab–to–RT-LAMP data.
T455 1710-1791 Sentence denotes V.L.D.T., K.H., P.C., L.P.M.K., M.K., and S.A. analyzed and interpreted the data.
T456 1792-1873 Sentence denotes V.L.D.T., K.H., M.K., and S.A. wrote the manuscript, with input from all authors.
T457 1874-1926 Sentence denotes Competing interests: P.S. has consulted for Janssen.
T458 1927-1991 Sentence denotes The other authors declare that they have no competing interests.
T459 1992-2024 Sentence denotes Data and materials availability:
T460 2025-2113 Sentence denotes All data associated with this study are in the main text or the Supplementary Materials.
T461 2114-2282 Sentence denotes The R code used to perform analyses and produce figures can be found on GitHub, together with all raw data tables: https://github.com/anders-biostat/LAMP-Paper-Figures.
T462 2283-2504 Sentence denotes This work is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
T463 2505-2587 Sentence denotes To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
T464 2588-2789 Sentence denotes This license does not apply to figures/photos/artwork or other content included in the article that is credited to a third party; obtain authorization from the rights holder before using this material.
T465 2791-2814 Sentence denotes SUPPLEMENTARY MATERIALS
T466 2815-2875 Sentence denotes stm.sciencemag.org/cgi/content/full/scitranslmed.abc7075/DC1
T467 2876-2897 Sentence denotes Materials and Methods
T468 2898-2906 Sentence denotes Fig. S1.
T469 2907-2927 Sentence denotes Design of the study.
T470 2928-2936 Sentence denotes Fig. S2.
T471 2937-3039 Sentence denotes Comparison of the RT-LAMP assay with CT values from RT-qPCR using primer sets E-Sarbeco and N-Sarbeco.
T472 3040-3048 Sentence denotes Fig. S3.
T473 3049-3158 Sentence denotes Comparison of the RT-LAMP assay using primer set 1a-A with CT values from RT-qPCR using primer set E-Sarbeco.
T474 3159-3167 Sentence denotes Fig. S4.
T475 3168-3202 Sentence denotes Analysis of LAMP-sequencing reads.
T476 3203-3211 Sentence denotes Fig. S5.
T477 3212-3255 Sentence denotes Sample classification with LAMP-sequencing.
T478 3256-3264 Sentence denotes Fig. S6.
T479 3265-3362 Sentence denotes RNA stability and detection limit of the RT-LAMP assay in pharyngeal swab specimens with IVT RNA.
T480 3363-3371 Sentence denotes Fig. S7.
T481 3372-3435 Sentence denotes Swab–to–RT-LAMP assay titration of positive COVID-19 specimens.
T482 3436-3445 Sentence denotes Table S1.
T483 3446-3500 Sentence denotes Sequences of primers and amplicons used in this study.
T484 3501-3510 Sentence denotes Table S2.
T485 3511-3572 Sentence denotes Sensitivity and specificity of the RT-LAMP test from Fig. 3B.
T486 3573-3582 Sentence denotes Table S3.
T487 3583-3644 Sentence denotes Sensitivity and specificity of the RT-LAMP test from Fig. 5B.
T488 3645-3654 Sentence denotes Table S4.
T489 3655-3688 Sentence denotes Primers used for LAMP-sequencing.
T490 3689-3698 Sentence denotes Table S5.
T491 3699-3763 Sentence denotes Overview of time requirements for various sample handling steps.
T492 3764-3777 Sentence denotes Data File S1.
T493 3778-3796 Sentence denotes Raw data for figs.
T494 3797-3807 Sentence denotes S6 and S7.
T495 3809-3866 Sentence denotes View/request a protocol for this paper from Bio-protocol.