Id |
Subject |
Object |
Predicate |
Lexical cue |
T67 |
0-4 |
Sentence |
denotes |
2.4. |
T68 |
5-79 |
Sentence |
denotes |
Identification of Previously Described Epitopes in CoV-2 Conserved Regions |
T69 |
80-381 |
Sentence |
denotes |
To identify previously reported epitopes in the conserved regions of coronaviruses (pan-coronavirus, betacoronaviruses, and human coronaviruses), and match them with the SARS-CoV-2 consensus sequence, searches for experimentally described epitopes were carried out in the Immune Epitope Database [54]. |
T70 |
382-449 |
Sentence |
denotes |
The search criteria were as follows: “linear peptide; blast option: |
T71 |
450-460 |
Sentence |
denotes |
90%; Host: |
T72 |
461-543 |
Sentence |
denotes |
Homo sapiens; Any MHC restriction; Positive assays only; All assays; Any disease”. |
T73 |
544-661 |
Sentence |
denotes |
The search yielded 141 epitopes, of which 14 B-cell epitopes and 2 epitopes from a hypothetical protein were removed. |
T74 |
662-782 |
Sentence |
denotes |
The remaining identified epitopes were subsequently used to generate an epitope map of the respective conserved regions. |