PMC:7560789 / 8176-9438 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T65 0-154 Sentence denotes A bronchoscopy with BAL is the preferred diagnostic approach because GM antigen detection and culture have a good sensitivity in influenza-associated IPA.
T66 155-420 Sentence denotes However, given the risk of aerosolization, The American Association for Bronchology and Interventional Pulmonology issued a statement providing a limited role for bronchoscopy in patients with COVID-19, advocating the use of a nonbronchoscopic alveolar lavage (10).
T67 421-546 Sentence denotes The technique we used in this study minimizes the risk for care providers while providing a diagnostic tool for our patients.
T68 547-620 Sentence denotes However, the nondirected BAL technique is not validated for GM detection.
T69 621-895 Sentence denotes As all patients had consolidations in all regions of the lung, the chances that a nondirected BAL may result in sampling of a lung region that was not affected by IPA may be low, although it is unclear to which extent consolidations are caused by the virus or by the fungus.
T70 896-1029 Sentence denotes More importantly, we cannot rule out overdiagnosis, as a nondirected sample may not always reflect microbiology of the lower airways.
T71 1030-1108 Sentence denotes Therefore, instead of 0.5, a cutoff GM index of 1.0 was applied in this study.
T72 1109-1158 Sentence denotes Nevertheless, sampling error cannot be ruled out.
T73 1159-1262 Sentence denotes Of note, however, concordance between GM index >1.0 and positive Aspergillus cultures was high (77.8%).