LitCovid-sentences  

PMC:7558914 / 11841-13524 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T77 0-186 Sentence denotes All protocol considered the management of ARDS with signs of cytokine release syndrome, which included elevation of interleukin-6, fibrinogen, D-dimer, and C-reactive protein levels [9].
T78 187-340 Sentence denotes The therapies (corticosteroids, anticytokine or immunomodulatory agents, and immunoglobulin therapy) were recommended once these syndromes were observed.
T79 341-440 Sentence denotes The choice of which therapy to use was made by physicians according to their own clinical judgment.
T80 441-574 Sentence denotes Corticosteroids were widely included in all protocols; indeed, only 2 out of 15 hospitals did not include any corticosteroid regimen.
T81 575-686 Sentence denotes There was a total of five corticosteroid regimens, which used dexamethasone, methylprednisolone, or prednisone.
T82 687-764 Sentence denotes Dexamethasone was recommended in eight protocols with two different regimens:
T83 765-812 Sentence denotes 20 mg (5/8, 62.5%) or 40 mg (3/8, 37.5%) daily.
T84 813-887 Sentence denotes Methylprednisolone was included in 13 protocols with 2 different regimens:
T85 888-944 Sentence denotes 125–250 mg (8/13, 61.5%) or 1 mg/kg (5/13, 38.5%) daily.
T86 945-1020 Sentence denotes Only one protocol included prednisone with a single regimen of 40 mg daily.
T87 1021-1119 Sentence denotes The duration of treatment varied from 3 to 10 days, depending on the patient’s clinical condition.
T88 1120-1227 Sentence denotes Tocilizumab was recommended in all protocols with the same dosage (400 or 600 mg) according to body weight.
T89 1228-1297 Sentence denotes Anakinra was included in seven protocols with six different regimens.
T90 1298-1367 Sentence denotes Immunoglobulins were included as possible therapy in three protocols.
T91 1368-1552 Sentence denotes In six protocols, other optional therapies were included, such as sarilumab, baricitinib, colchicine, ciclosporin A, sirolimus, tacrolimus, and vitamin D, according to clinical trials.
T92 1553-1683 Sentence denotes Dosage and durations of corticosteroids, anticytokine or immunomodulatory agents, and immunoglobulin therapy are shown in Table 3.