PMC:7558333 / 10771-12074 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T85 0-4 Sentence denotes 3.3.
T86 5-36 Sentence denotes Concordance of Diagnostic Tools
T87 37-114 Sentence denotes Table 4 gathers the results of the techniques used for Aspergillus detection.
T88 115-257 Sentence denotes DNA detection by PCR showed the highest sensitivity, with a number of positive respiratory samples near twice higher, compared to the culture.
T89 258-492 Sentence denotes Only one sample grew in culture, whereas PCR was negative, but the species obtained in culture was A. tubingensis (Nigri complex species), which is theoretically not amplified when using the 28S-targeted PCR specific for A. fumigatus.
T90 493-752 Sentence denotes Interestingly, the correlation between cultural and molecular quantification showed a significant difference between the two techniques, with a mean Cq threshold of 32.6 ± 0.7 when cultures were negative, highlighting the higher sensitivity of PCR (Figure 1).
T91 753-890 Sentence denotes Overall, the concordance coefficient between PCR and culture on respiratory samples was 90.52% with a Cohen’s Kappa coefficient of 0.588.
T92 891-980 Sentence denotes Regarding blood samples, three patients had a positive detection of a systemic biomarker:
T93 981-1040 Sentence denotes 3/3 had a positive PCR and 2/3 had a positive GM (Table 5).
T94 1041-1165 Sentence denotes All three patients had a simultaneous detection of Aspergillus in respiratory samples by culture (n = 2) and/or PCR (n = 3).
T95 1166-1303 Sentence denotes Overall, the concordance coefficient between PCR and culture on respiratory samples was 93.75% with a Cohen’s Kappa coefficient of 0.632.